Protein Alignment Ir40a and Nmdar1

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 484
• Identity: 100/484 - (20%)
• Similarity: 189/484 - (39%)
• Gaps: 117/484 - (24%)

  Fly   265 LLMLLSKHMNFRFKYIEAPGRTQGS--MRSEDGKDS-NDSFTGGIGLLQSGQADFFLGDVGLSWE 326
            ||:.|||.:||.:....:|....|.  :|:..|..: ...:||.||.|.:.:||..:..:.::.|
  Fly   472 LLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPE 536

  Fly   327 RRKAIEFSFFTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIW 391
            |.:.||||..............|.|.:..::.::||...:|..:::::.....:.|.:.......
  Fly   537 RAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFG 601

  Fly   392 RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCN 456
            |.:.::||...               .:.|.|                ...:||...:.|.....
  Fly   602 RFKLSHSDSNE---------------EKALNL----------------SSAVWFAWGVLLNSGIG 635

  Fly   457 E-LHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPI---------NTLQRLQAAMI 511
            | ....:.|:.|.:| |.....::...|:|.|.:.......:..:         ||::.|..|.:
  Fly   636 EGTPRSFSARVLGMV-WAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATV 699

  Fly   512 HDGYRLYVEKESSSLEM-------LENGTELFRQL----YALMRQQVINDPQGFFIDSVEAGIKL 565
                      :.||::|       |.|   ::|.:    ||...|.:.:..:|..:..:....:|
  Fly   700 ----------KGSSVDMYFRRQVELSN---MYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRL 751

  Fly   566 IAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESG 630
            ..|..:|..::...|  .|....||                :.:|.|.|:..::...:::..|||
  Fly   752 EYEASKDCELVTAGE--LFGRSGYG----------------IGLQKGSPWTDAVTLAILEFHESG 798

  Fly   631 ILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGS 695
            .::|:.     ||:       |:.|.|| :|.|.:.:|.       :.|.|:.:.|.||.:|||
  Fly   799 FMEKLD-----KQW-------IFHGHVQ-QNCELFEKTP-------NTLGLKNMAGVFILVGVG- 842

  Fly   696 LAAGV-ILLLEIVFIK--------LDQAR 715
            :|.|| ::::|:::.|        ||.||
  Fly   843 IAGGVGLIIIEVIYKKHQVKKQKRLDIAR 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	24/73 (33%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	19/94 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	28/160 (18%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	81/421 (19%)
		CaM_bdg_C0	854..882	CDD:402271	5/18 (28%)