Protein Alignment Ir40a and Nmdar2

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 98/471 - (20%)
• Similarity: 171/471 - (36%)
• Gaps: 119/471 - (25%)

  Fly   278 KYIEAPGRTQGSMRSEDGK---DSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLA 339
            |:.|..|.|...:|.||||   ..|..:.|.|..|.:.:.|..|..:.::.||...::|| ....
  Fly   573 KFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFS-EPFM 636

  Fly   340 DSGAFATHAPRR-LNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALP----YIWRRRWANSD 399
            ::|.....|.|. :....|.:.||....|            :..||:|:.    .|:...|.:..
  Fly   637 ETGIAIVVAKRTGIISPTAFLEPFDTASW------------MLVGIVAIQAATFMIFLFEWLSPS 689

  Fly   400 VEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCN-ELHNGYR 463
            ...: :||:..|   .:||....|                .:..|....:..:.:.: :...|:.
  Fly   690 GYDM-KLYLQNT---NVTPYRFSL----------------FRTYWLVWAVLFQAAVHVDSPRGFT 734

  Fly   464 AKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEM 528
            ::|:|.|:.:.|...|| :|:|.|.:...........:.|.  .:.::|.    :..|.|
  Fly   735 SRFMTNVWALFAVVFLA-IYTANLAAFMITREEFHEFSGLN--DSRLVHP----FSHKPS----- 787

  Fly   529 LENGT-----------ELFRQLYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETL 582
            .:.||           :.|..::..|||        :...||..|:..:..|..|..:..| ..|
  Fly   788 FKFGTIPYSHTDSTIHKYFNVMHNYMRQ--------YNKTSVADGVAAVLNGNLDSFIYDG-TVL 843

  Fly   583 FFNVQQ------------YGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKM 635
            .:.|.|            |....:.|:....::|    ||:       .|..|::...:|.|:::
  Fly   844 DYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKY----VQM-------FNKRLLEFRANGDLERL 897

  Fly   636 TAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGV 700
                  ::|......|  .|..:.|:|:              ||.|.....||:.|..|.|.|.:
  Fly   898 ------RRYWMTGTCR--PGKQEHKSSD--------------PLALEQFLSAFLLLMAGILLAAL 940

  Fly   701 ILLLEIVFIKLDQARL 716
            :||||.|:.|..:.||
  Fly   941 LLLLEHVYFKYIRKRL 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	19/60 (32%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	20/98 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	28/163 (17%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	78/407 (19%)