Protein Alignment Ir40a and gria3a

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 791
• Identity: 152/791 - (19%)
• Similarity: 278/791 - (35%)
• Gaps: 215/791 - (27%)

  Fly    64 QKERNVYLDDFLQRLHRSNYKSVVFSQTELFFQHIEENLQGANECISLILD-----EPNQLLNSL 123
            ::|:...:|..::|::....:.|:..:....:.:|..||...|..:..:..     ...|::|.
Zfish   205 RQEKRFLIDCEVERINSILEQVVIAGKNSRGYHYILANLGFTNMSLDKVFSGGANITGFQIINP- 268

  Fly   124 HDRHLGHRLSLFIFYW---GARWPPSSRVIRFREPLR---------VVVVTRPRKKAFRIYYNQ- 175
             |..:   :..|:..|   ..|..|.||    ..||:         ::|:.    :|||....|
Zfish   269 -DSPI---VQQFLQRWERLDEREFPESR----SSPLKYTSALTHDAILVIA----EAFRYLRRQR 321

  Fly   176 -------------ARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFK----GR--TFRVP 221
                         |.|.       |.|..|  :.::|...:.....:..|.:    ||  .:.|.
Zfish   322 VDISRRGSAGDCLANPA-------VPWSQG--IDIERALKMVQVQGMTGNIQFDSFGRRSNYTVD 377

  Fly   222 VFHSPP------WFWVTYCNNSFE------EDEEFNSLDSIEKRKVRVT---------------- 258
            |:...|      .:|     |.||      |.:..|...|:|.|.:.||
Zfish   378 VYEMKPGGARKIGYW-----NEFEKFVYIVEQQVTNESSSVENRTIVVTTIMEAPYVMYKRNYMQ 437

  Fly   259 -GGRDH------RLLMLLSKHMNFRFKY-IEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQAD 315
             .|.|.      .|...::||:..::|. |.|.|: .|:...|     ..::.|.:|.|..|:||
Zfish   438 LEGNDRYEGYCVDLASEIAKHVGIKYKLSIVADGK-YGARDPE-----TKTWNGMVGELVYGRAD 496

  Fly   316 FFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTIIFS 377
            ..:..:.::..|.:.|:||  |.:|..|  .....|::....: :.:.|...:||    :.|:|:
Zfish   497 IAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFA 555

  Fly   378 GPIFYGIIAL--------PYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQM 434
               :.|:..:        ||.|          ||.:        .|.|.     .|:|   ....
Zfish   556 ---YIGVSVVLFLVSRFSPYEW----------HLDD--------NEETK-----DPQT---PPDP 591

  Fly   435 PHQ--LFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPARE 497
            |:.  :|.. :||:|..|::|.|:........:.:..|:|. .|.::...|:|.|.:........
Zfish   592 PNDFGIFNS-LWFSLGAFMQQGCDISPRSLSGRIVGGVWWF-FTLIIISSYTANLAAFLTVERMV 654

  Fly   498 PPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGT--ELFRQ----LYALMRQQVINDPQGFFI 556
            .||.:.:.|            .::...:...|::|:  |.||:    :|..|...:.:.....|:
Zfish   655 SPIESAEDL------------AKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFV 707

  Fly   557 DSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNN 621
            .:...|:..:.:.....|.|.......:..|:...:..::...|.::...||...|.....::|.
Zfish   708 KTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRSAVNL 772

  Fly   622 VLMQLFESGILDKM-------------------------TAAEYAKQYQEVEATRIYKGSVQA-- 659
            .:::|.|.|:|||:                         |.:.:....:......:.|.|.|.
Zfish   773 AVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKHKARCPTVSLWLTDIRTPVNLAVLKLSEQGIL 837

  Fly   660 ---KNSEAYSRTE-------SYDSTVISPLNLRMLQGAFIALGVGSLA-AGVILLLEIVFIKLDQ 713
               ||...|.:.|       |.|.|  |.|:|..:.|.|..| ||.|. |..:.|:|..:....:
Zfish   838 DKLKNKWWYDKGECGTKDSGSKDKT--SALSLSNVAGVFYIL-VGGLGLAMTVALVEFCYKSHQE 899

  Fly   714 ARLWMLCSRLQ 724
            .:...|....|
Zfish   900 TKRLKLAKNAQ 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	19/73 (26%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	22/104 (21%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	26/171 (15%)
gria3a	XP_073805840.1	None