Protein Alignment Ir40a and grin2ba

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001429729.1
• Gene: grin2ba / 110438919
• ZFINID: ZDB-GENE-090821-2
• Length: 1606
• Species: Danio rerio
• Alignment Length: 676
• Identity: 122/676 - (18%)
• Similarity: 220/676 - (32%)
• Gaps: 224/676 - (33%)

  Fly    85 SVVFSQTELFFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWG--ARWPPSS 147
            :|.|....|.|.  |:..|...:.:.::||:..|                    |.  .:|...|
Zfish   392 NVTFEGRNLSFS--EDGYQMHPKLVIILLDKERQ--------------------WDRVGKWENGS 434

  Fly   148 RVIRFREPLRVVVVTRPRKKAFRIYYN-QARPCSDSQLQLVNWYDGDNLGLQRI-PLLPTALSVY 210
            ..:::.        ..||   |.:|.. :||  .|..|.:|...:...:.::.: ||..|.:
Zfish   435 LSMKYH--------VWPR---FELYSGPEAR--EDDHLSIVTLEEAPFVIVEDVDPLSGTCM--- 483

  Fly   211 ANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKV---RVTGGRDHRLLMLLSKH 272
                                    .|:....::..:|:..:...|   |...|....:|..::|:
Zfish   484 ------------------------RNTVPCRKQLKALNQTQDSAVYIKRCCKGFCIDILKKIAKN 524

  Fly   273 MNFRFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSF- 335
            :.|.:. |:...|:        .||..|.::.|.:|.:....|...:|.:.::.||.:.|:||.
Zfish   525 VKFTYDLYLVTNGK--------HGKKINGTWNGMVGEVVLKNAHMAVGSLTINEERSEVIDFSVP 581

  Fly   336 -----FTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRW 395
                 .::..|.:..|.:|.      |.:.||..|:|..:.:.::....|...|.
Zfish   582 FIETGISVMVSRSNGTVSPS------AFLEPFSADVWIMMFVMLLLVSAIAVFIF---------- 630

  Fly   396 ANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQM--PHQLFQKCIWFTLRLFLKQSCNEL 458
                     |.:..:.|            .|.:....:.  |.....|.||....|....|. .:
Zfish   631 ---------EYFSPVGY------------NRCLADGREAGGPSFTIGKAIWLLWGLVFNNSV-PV 673

  Fly   459 HN--GYRAKFLTIVYWIAATYVLADVYSAQLTS-----------------QFARPAR-EPPI--- 500
            .|  |..:|.:..|:...|...||. |:|.|.:                 :|..|.. .||.
Zfish   674 QNPRGTTSKIMVSVWAFFAVIFLAS-YTANLAAFMIQEEYVDQVSGLSDKKFQNPNDFSPPFRFG 737

  Fly   501 ------------NTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQG 553
                        |..:.:.:.|:....|..||    :||.|:.| :|...:|   ...|:|
Zfish   738 TVPNGSTERNIRNNYRDMHSYMVKFHQRNVVE----ALESLKTG-KLDAFIY---DAAVLN---- 790

  Fly   554 FFIDSVEAGIKLIAEG-GEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLG 617
             ::...:.|.||:..| |:..|..|           ||                :|:|....:..
Zfish   791 -YMAGRDEGCKLVTIGSGKVFASTG-----------YG----------------IAIQKDSGWKR 827

  Fly   618 SLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLR 682
            .::..::|||..|            :.:|:||..: .|....:.:|..|          |.|::.
Zfish   828 QVDLAILQLFGDG------------EMEELEALWL-TGICHHEKNEVMS----------SQLDVD 869

  Fly   683 MLQGAFIALGVGSLAAGVILLLEIVF 708
            .:.|.|..||.....:.:..:.|.||
Zfish   870 NMAGVFYMLGAAMALSLITFIAEHVF 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	17/77 (22%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	20/99 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	30/157 (19%)
grin2ba	NP_001429729.1	None