Protein Alignment CG42748 and Ajm1

DIOPT Version :10

• Sequence 1: NP_001260684.1
• Gene: CG42748 / 35442
• FlyBaseID: FBgn0261802
• Length: 2190
• Species: Drosophila melanogaster
• Sequence 2: NP_001005424.2
• Gene: Ajm1 / 381353
• MGIID: 2685842
• Length: 974
• Species: Mus musculus
• Alignment Length: 1058
• Identity: 240/1058 - (22%)
• Similarity: 369/1058 - (34%)
• Gaps: 322/1058 - (30%)

  Fly  1320 LNVNSVAYDVDELDAEVKPSPGGMASVRRP-----------------H-KSMEFL--LDK---EN 1361
            |.|::|..|:..:|.       |:.|.|:|                 | :|.:||  ||:   |.
Mouse     9 LLVSTVYQDIKVVDP-------GLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMET 66

  Fly  1362 QKNILPPENELQKSHDHNPGALSEHQLRVQASLQRLNIPDWFRHYNKGPEKAADGENACTSATGG 1426
            .....|||....::...:    ||.:.|.:               :|...:|:.|.....::...
Mouse    67 HPEPPPPEPAPPRARPRD----SEPRRRTR---------------SKSAPRASQGLATAPASPPV 112

  Fly  1427 GYRPGNFTRKRAQESGRWQGLNSKTTSLSSLGSQRSDRSPLLMSP-------------------- 1471
            ..|.|    :.||.:.|.:|...:..|..:|.:..::..|:.:.|
Mouse   113 LQRRG----REAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAP 173

  Fly  1472 --------------------SAHSHHGGQSSYSCG--STT--------IHG---PAPVQIGMGAT 1503
                                .|...|..:||.||.  .||        .||   |.|..:.:..|
Mouse   174 PEPPSGPVPHVRCRLDIKPDEAVLQHAARSSRSCAPRETTSWARTAPQFHGLTVPGPRHVALSRT 238

  Fly  1504 RWSTSHLNSTQ-------------------------MSPGASQ----------RGSFTRGAPINS 1533
            . :.|.|..|.                         ..||.:|          .||||
Mouse   239 P-TPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFT------- 295

  Fly  1534 SFISVASGSGLLRNSYRQPYLGWRSTEKLSQRTPHERLANSLLTQRTAPPSTRAG-----NETRT 1593
                  :..||       |:.|:.|...||:..|.              ||.|.|     .|.||
Mouse   296 ------TSPGL-------PFDGYCSRPYLSEEPPR--------------PSPRRGGSYYAGEVRT 333

  Fly  1594 LHSVSTEIQSSIKEVTSA-----IVHFVNDQQQSQHPRSRS-----------------TSPNSRC 1636
            ........:|...|.|.|     :..:|.::.:: ||.:|:                 |.|:.|.
Mouse   334 FPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRA-HPGARTFYTEDFGRYRERDVLARTYPHPRS 397

  Fly  1637 ---WLESSFVGTRTLDSPQTPV-----------IDNSPPELARKQQQLHPHQVHLDVGLSPVVSA 1687
               |.:......|||.....|.           ...|||.||...:       |.......:::.
Mouse   398 SPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSR-------HYSRSWDNILAP 455

  Fly  1688 GQLPHRMNGINR-------IGNGGVPTRNIAPE--------------RSLSSASLEDVLASLLGL 1731
            |  |.|.:.:.|       :|.....||..:||              |..::.||.:...:..|.
Mouse   456 G--PRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGR 518

  Fly  1732 PTTLLSGQN--SNSYSSYTPNAATTACAASRQQLEVQSAAELQRLRRRSEGDAPTQEKHYSKEQS 1794
            ....| |:|  .....:.|.|...:....:.:..|:......|.:....||.|.::::  |.||.
Mouse   519 AGESL-GRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQR--SLEQL 580

  Fly  1795 HKSNSHSVEAVDSAQPNNPKE---------------SRRASLGDPA-LAATRS---DIGSGQLQL 1840
            .:..:..|  :||..|....|               ||.|..|... ||.:||   ..||
Mouse   581 DELITDLV--IDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGS----- 638

  Fly  1841 IEGPTTGFGSGQH--------------VRCRNTKCDQSTSPSDAKKLYKSCHNCSHLYCSRECRR 1891
            .|.||   |||:.              :.|.|.:|.::.:..:|...:||||:|...||||.|||
Mouse   639 TEEPT---GSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRR 700

  Fly  1892 AHWEKHRKACLHSRASNICRQVLATCKDDIDSQRHLSLLARKGSLSQGRGVVRVLFRSAEAAEGF 1956
            ..|:.|:..|::.|..::||.||..|:|.....|..|.:||.|.||:||||:.:.|.|..:|:.|
Mouse   701 EDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNF 765

  Fly  1957 IKNGFQ-CMGEASYVRWPDLMPAEMGLELYS-ELLKLSTEYKPETKMLIYVAICVVSEA--PGMG 2017
            ::.|.: .:...:|:...:|......|..|: ||......|:|....|:.|::.|...|  ||..
Mouse   766 LRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAA 830

  Fly  2018 QAPV-RWERQLVSRCAKLKLCKTVLAELEQHQAALLQPVSVVAVPERTEILILTFNPGQ------ 2075
            ..|. |.....|.:.||:.|.          ..:..:|..........|.||||..||.
Mouse   831 ARPAPRTPGPTVRKFAKVALA----------AGSPTRPPPARGGEPDMETLILTPPPGTAGLDEE 885

  Fly  2076 ----HSNRELILSNILDILSRRGVMLSKHYPEVFERLQTYSEGQSDKFNPVTLHPRDTQTGQNFV 2136
                ...||:...:|...|..|||.|...:|.|:|:|..:.|. :.:|.|.|::|.|.:||:.|:
Mouse   886 GEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEA-NRRFTPTTIYPTDRRTGRPFM 949

  Fly  2137 CIIMAVHTDNELTKLPSA 2154
            |:|||......|..:.||
Mouse   950 CMIMAASEPRALDWVASA 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42748	NP_001260684.1	zf-MYND	1870..1901	CDD:460312	15/30 (50%)
Ajm1	NP_001005424.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..137		27/143 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..233		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..326		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	539..576		5/38 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	618..661		14/50 (28%)
		zf-MYND	667..710	CDD:460312	17/42 (40%)