Protein Alignment CG11630 and R03G8.1

DIOPT Version :10

• Sequence 1: NP_610124.1
• Gene: CG11630 / 35429
• FlyBaseID: FBgn0032964
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_510172.2
• Gene: R03G8.1 / 187544
• WormBaseID: WBGene00010996
• Length: 663
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 150/713 - (21%)
• Similarity: 248/713 - (34%)
• Gaps: 179/713 - (25%)

  Fly    11 LYSLIIFSFVYYYN-------------DVVVDNIIFEEHHLVEKYSVDTKGCRMLTMVPNEYDVM 62
            ||.|:..:|.|..:             |::|.|            |.||  |.:     ..|||
 Worm    18 LYILVCIAFTYSVSIVIHTDYAAPVTEDILVGN------------SWDT--CEL-----PRYDV- 62

  Fly    63 FLWRGLRRDFCASNLNL-----TSFSNCTYNYLRTEVNMELAKARFGVETLESFKCMYYAMERHT 122
              |......:...|.|.     |||...|          :|..:::||....:..|......|..
 Worm    63 --WDEELFGYLNPNENPLKKCDTSFKPLT----------KLENSKWGVTFAHNLTCRARCHTRKR 115

  Fly   123 DFDNRYLYSREFELLTDGNNTIEP---HADIIRAECFINA---TSIYNGVHFYVHPTDEWLRTAQ 181
            |.:|..           ||.|..|   :.:|:...|....   ..:|..:|..:.||.
 Worm   116 DKENLV-----------GNWTYTPGKINCEILETVCAEKGGEQRDVYGYLHSQIIPTK------- 162

  Fly   182 GLPPL-KLASDVGSLSVLIVGLDSISQMHFHRSMARTANFLLSLPHVELKG-----FNRLGEDG- 239
              |.| :..:|:....|.::.|||:|.....||:.||.:|..|.    :||     .|::|::.
 Worm   163 --PKLSRTNADLKEYDVFVILLDSLSYSQAARSLPRTVSFFKSY----MKGIIFPYMNKVGDNSR 221

  Fly   240 -------FDSLMPLLS-------GLSGQELKDVSSNLSSLDSCPFIWKVFQKAGYETGLGEDNID 290
                   |..|:..:.       .|......|...|:.. |:...::..|:..||:|.:.||...
 Worm   222 PNGVALWFGKLLEKVDRFIFDKPSLEADWTDDYFCNVFK-DNETSLFDEFKTHGYKTLMAEDWAL 285

  Fly   291 KSLF---VKGFRKPPTDFYLRPALL---EMWLKTRTDGLFGTHCNEKDNYAMVLREFLFKML--- 346
            .:|.   ..|:|....|.|:||..|   :.......:.|.|:.|.|..|   .|.::|.:.|
 Worm   286 GTLIWPNCLGYRNQSIDHYMRPFQLAHEKYGTPVTREHLNGSLCREDHN---TLLDYLAQFLDAY 347

  Fly   347 --------------PHHTSHRFFTFLWWTQ-------GIDHLFNYGRKLDQPFLKMFKAIGRSGL 390
                          |:....|.|.|||.|:       |.|...|..   |..||..|  |.....
 Worm   348 SGSNDSIQLKREKSPNSPDQRKFAFLWTTRLGHATENGFDATENGS---DNDFLNFF--IKHRKK 407

  Fly   391 LKNTVLLVVSNHGLNKGRFYKTVQGKVEESQPLAILCYPRWLEERYPQAIGNLKSNNRRLVTAFD 455
            |:::.:|::.:||...|....|..|.::.:.||..:..|..|... ...:..|..|:.:|.|.||
 Worm   408 LEDSFVLLLGDHGFRLGGVRNTAVGAIDVNNPLTAISVPNSLRTN-TDILKILNMNSEKLQTHFD 471

  Fly   456 LHATLQNLPNLTSLEDEQLQQRRVDLWAMGKDIPRGISLFLPI---------------PDHRDCF 505
            ..||:.::......|.                    .|...|:               |.:|:|.
 Worm   472 TRATILDILKFQPAEK--------------------FSAITPLQIPGEKGQSHLRNQPPFNRNCQ 516

  Fly   506 LAAIPTANCLCQ-QPRNVSTSDGYVQRAARLIIRNLNKM--IHTHTPPCKTLYLDRVLTADKWRR 567
            ...||...|:|| ...:|..:..........:..|:||:  |:..|..|.::..:|..:..::.:
 Worm   517 TMPIPFEYCICQFNKTSVPINSTISMEIGEKVAENVNKLLQINNFTSECISMVFERTESLLQYNQ 581

  Fly   568 IADEHQSEFRVRLIATPGEGQFEGIVRYTGYKLAVDGHISRVNDYRNGSQCIRNYLIEMYCFC 630
            ..........:..:..|.|.:|:..|:.|...:.:...:.||:.|...:.||.:......|:|
 Worm   582 KLGNSTIYTVIAQMKKPSEAKFKATVKITEGNIKIVSKVERVDSYGKTADCIESETHRPICYC 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11630	NP_610124.1	DUF229	66..560	CDD:397236	122/573 (21%)
R03G8.1	NP_510172.2	DUF229	74..651	CDD:397236	134/635 (21%)