DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and CG10654

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	83/399 - (20%)
Similarity:	141/399 - (35%)	Gaps:	124/399 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 DVNAKCSNSRKTIESSQRLAQ------HQAEVHS-----------------SDNHL-CLSCG--- 658
            |....|:.|.:..|   :|.|      |:.|.|:                 :.:|. |::..
  Fly   100 DFQRMCAESLRNFE---KLLQDIDIGCHKLEDHTWHDLDTPSESNESTNPEAQSHAPCIAATQEI 161

  Fly   659 ISFESAQALGRHTRSCQPLASTSTPADLSQAQKKSMYSC-DQCRFQSQYESDL-VYHRIFHTRSG 721
            :||...|.       |.|||...:...|..:.::.:|.. |:...|...:..| :..::...|..
  Fly   162 VSFIWPQV-------CLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKR 219

  Fly   722 TIGKNEVLQCPLCPKNFKKHS-LRAHLRNHTNEKIFECTECLQKFARRHNLKNHVITKHAKVGDK 785
            . |....|:|.:|.:.|.|.| |.||::.|...:.:.|..|.:.:||.:.|::|:...|
  Fly   220 R-GVRHTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMH------ 277

  Fly   786 EKKKYAAKDVEQSKPKYQCGTCGKLLAKKYSLKLHEISHSKAVERNYLCHFADCSYAGRTPESLK 850
                   .:.:.::..|.|.:|.|:.....|||.|                           ..:
  Fly   278 -------NNADAARIIYACPSCNKVYTANRSLKYH---------------------------MRR 308

  Fly   851 THLVSHSQENHKCARINCSYVGKSELHLKRHLKSAHSTEKNGEEWFSCDQCDFRARIKGHLRRHS 915
            ||...|..|:...                ||:               |::|......|.||.||.
  Fly   309 THERYHESESPDA----------------RHI---------------CEECGKCFARKAHLTRHK 342

  Fly   916 LRHSGQKPHQ--CPHCDFQCSTIDNLRKHIIKTGKHPGM-FIYHCAKCSDEEAGEIFKSNSYKEY 977
            :.|...:..:  |..||.:..|.:|:..|:::  ||... .:..|.||     |.||:::  .|.
  Fly   343 MVHGSVEGRRYCCECCDRRFYTKENMVDHLLR--KHGNKNLLLRCRKC-----GRIFQNS--VEL 398

  Fly   978 QHHLKTHKA 986
            ..|.:.|||
  Fly   399 NAHGRKHKA 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	3/21 (14%)
		C2H2 Zn finger	731..750	CDD:275368	8/19 (42%)
		C2H2 Zn finger	758..779	CDD:275368	6/20 (30%)
		C2H2 Zn finger	804..824	CDD:275368	7/19 (37%)
		C2H2 Zn finger	834..856	CDD:275368	2/21 (10%)
		C2H2 Zn finger	898..918	CDD:275368	7/19 (37%)
		zf-H2C2_2	910..935	CDD:290200	8/26 (31%)
		C2H2 Zn finger	926..945	CDD:275368	6/18 (33%)
		C2H2 Zn finger	957..984	CDD:275368	8/26 (31%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	4/17 (24%)
		C2H2 Zn finger	228..248	CDD:275368	8/19 (42%)
		C2H2 Zn finger	256..313	CDD:275368	17/96 (18%)
		C2H2 Zn finger	289..314	CDD:275368	9/51 (18%)
		zf-C2H2	323..345	CDD:278523	8/36 (22%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..376	CDD:275368	6/22 (27%)
		C2H2 Zn finger	385..405	CDD:275368	8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100