Protein Alignment step and plekha2

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001121835.1
• Gene: plekha2 / 100003662
• ZFINID: ZDB-GENE-081105-163
• Length: 391
• Species: Danio rerio
• Alignment Length: 370
• Identity: 75/370 - (20%)
• Similarity: 131/370 - (35%)
• Gaps: 145/370 - (39%)

  Fly   384 LDVPEDCKHSNKDKQMSIGRKKFNMDPKK---------------GIEYLVENRL----------L 423
            ||:.|   :.|.|:   ..|:.|.:|..|               |.|::...||          |
Zfish    14 LDIEE---NENSDR---FSRRYFILDTDKNYLLWYMDNPQNLPVGTEHVGSLRLSYISKVNEASL 72

  Fly   424 RHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLP 488
            :..|:  |.|.:....|::.    |..:.|| ..|:.:..:|:::.|.:.:.:
Zfish    73 KQKPK--AEFCFVIHALSRR----YFLQAND-ALDLKEWVIAVNNATKITVPK------------ 118

  Fly   489 GEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPS---------------- 537
                         |...|| :.|:                  |::.|||
Zfish   119 -------------ASPVCQ-SSDV------------------TNVSNPSQSAPRQAYTTAIVGGV 151

  Fly   538 -----VKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKE 597
                 |:...:.|.|::     :.|..:|....:|      ..|                |..:.
Zfish   152 VVQTPVQQNDSEDVFMA-----DPGAHVPLRRCQS------ARP----------------NALRS 189

  Fly   598 GWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATG 662
            |:..|||...||||||:|||:|..:.|::...|||     ||.:|.:|::...::  |  |..:|
Zfish   190 GYCVKQGNVRKSWKRRFFILDDQTVSYYKSEMDKE-----PLRSIRLRDVLKVNE--C--LVKSG 245

  Fly   663 GADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSI 707
              |::   ..|:..:::....|.| :...|.||.:.||..:...|
Zfish   246 --DLL---SRDNLFEIITSARTFY-IQTDTPEDMKGWIMDIASKI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	33/225 (15%)
		PH_GRP1-like	592..710	CDD:269954	36/116 (31%)
		PH	596..708	CDD:278594	35/112 (31%)
plekha2	NP_001121835.1	PH-like	1..119	CDD:302622	24/142 (17%)
		PH	11..113	CDD:278594	23/111 (21%)
		PH2_TAPP1_2	179..294	CDD:270090	38/143 (27%)
		PH	188..280	CDD:278594	34/106 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910