Protein Alignment Lamp1 and LAMP5

DIOPT Version :10

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_036393.1
• Gene: LAMP5 / 24141
• HGNCID: 16097
• Length: 280
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 47/218 - (21%)
• Similarity: 83/218 - (38%)
• Gaps: 43/218 - (19%)

  Fly   113 TSCIMLQMAAQLNFTYEAREGNFTTGLYNIPSNASVEDAECKSQ---TTQFIHLIW--------- 165
            |:|:|.:.||:....|:....|:...:......|....||.|.:   :...:.:.|
Human    55 TTCLMAEFAAKFIVPYDVWASNYVDLITEQADIALTRGAEVKGRCGHSQSELQVFWVDRAYALKM 119

  Fly   166 -----------GPE-TSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDAKENQTVQLITRSDG 218
                       ||| |.:.|.:.:...|::.|              .|.||.........:....
Human   120 LFVKESHNMSKGPEATWRLSKVQFVYDSSEKT--------------HFKDAVSAGKHTANSHHLS 170

  Fly   219 AFKTPENMSYHCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFSVGHDC---DSSET 280
            |..||...||.|...|.|::..: |.::.:..| :|.|.::.|...:|..||..|.|   :..:.
Human   171 ALVTPAGKSYECQAQQTISLASS-DPQKTVTMI-LSAVHIQPFDIISDFVFSEEHKCPVDEREQL 233

  Fly   281 SDVVPIAVGIALAALILVVLISY 303
            .:.:|:.:|:.|..:|:|.|..|
Human   234 EETLPLILGLILGLVIMVTLAIY 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	106..262	CDD:480752	34/172 (20%)
LAMP5	NP_036393.1	Lamp	43..213	CDD:480752	35/173 (20%)