Protein Alignment Lamp1 and Lamp1

DIOPT Version :10

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001304282.1
• Gene: Lamp1 / 16783
• MGIID: 96745
• Length: 407
• Species: Mus musculus
• Alignment Length: 292
• Identity: 80/292 - (27%)
• Similarity: 130/292 - (44%)
• Gaps: 54/292 - (18%)

  Fly    36 KNVSDLFLEQANPLTSSSSTISTSST--TTEKPITTRSTSTITPRSTTPSTESPSTTAPVISTTI 98
            |||:.:..:.......||...|...|  |.:.|              :|:|..||.:.|::.|
Mouse   159 KNVTVVLRDATIQAYLSSGNFSKEETHCTQDGP--------------SPTTGPPSPSPPLVPT-- 207

  Fly    99 APQPYPQPSIGAWNT-----SCIMLQMAAQLNFTYEAREGNFTTGLYNIPSNASVEDAECKSQTT 158
                  .|::..:|.     :|::..||.|||.||..::....|..:||..| ......|.
Mouse   208 ------NPTVSKYNVTGNNGTCLLASMALQLNITYLKKDNKTVTRAFNISPN-DTSSGSCG---- 261

  Fly   159 QFIHLI-WGPETSKQSLIMYF--NKSNDTTVLSFMQIHLALLPEDFPDAKENQTVQLITRSDGAF 220
              |:|: ...|...::|.:.|  |.|:....|..:::::.|     |||.. .|..:...|..|.
Mouse   262 --INLVTLKVENKNRALELQFGMNASSSLFFLQGVRLNMTL-----PDALV-PTFSISNHSLKAL 318

  Fly   221 KTPENMSYHCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFSVGHDCDSSETSDVVP 285
            :.....||.|...:.|.:::.|.       ::|..|||:||:..:|...|| .:|.....:.::|
Mouse   319 QATVGNSYKCNTEEHIFVSKMLS-------LNVFSVQVQAFKVDSDRFGSV-EECVQDGNNMLIP 375

  Fly   286 IAVGIALAALILVVLISYLCARRRSTSRGYMS 317
            ||||.|||.|:|:|||:||..|:||.: ||.:
Mouse   376 IAVGGALAGLVLIVLIAYLIGRKRSHA-GYQT 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	106..262	CDD:480752	40/163 (25%)
Lamp1	NP_001304282.1	First lumenal domain	26..189		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..208		4/28 (14%)
		Hinge	190..219		5/28 (18%)
		Lamp	209..355	CDD:460152	37/153 (24%)
		Second lumenal domain	220..371		35/158 (22%)
		TM_EGFR-like	372..401	CDD:213052	10/28 (36%)