Protein Alignment dia and AT5G58160

DIOPT Version :10

• Sequence 1: NP_001246113.1
• Gene: dia / 35340
• FlyBaseID: FBgn0011202
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_001318825.1
• Gene: AT5G58160 / 835928
• AraportID: AT5G58160
• Length: 1266
• Species: Arabidopsis thaliana
• Alignment Length: 645
• Identity: 168/645 - (26%)
• Similarity: 286/645 - (44%)
• Gaps: 101/645 - (15%)

  Fly   488 AKAAHLEEKVKLMEANGVAAPSP------NKLPKVNIPMPPPPPGGGGAP---------PPPPPP 537
            |.:.||.....:....|..|.||      :|.|.:..|.|||||    .|         ||||||
plant   652 ATSPHLGASDNVASNLGQPARSPPPISNSDKKPALPRPPPPPPP----PPMQHSTVTKVPPPPPP 712

  Fly   538 MPG-------RAGGGPPPPPPPPMPG----RAGG-------PPPPPPPPGM----------GGPP 574
            .|.       .....||||||||.|.    ::.|       ||.||.||.:          ..||
plant   713 APPAPPTPIVHTSSPPPPPPPPPPPAPPTPQSNGISAMKSSPPAPPAPPRLPTHSASPPPPTAPP 777

  Fly   575 PPPMPGMMRPGGGPPPPPMMMG----------PMVPVLPHGLKPKKKWDVKNPMKRANWKAIVPA 629
            |||: |..|....|||||..:|          |..|.||.|  |....  |..|.|.|.|. .||
plant   778 PPPL-GQTRAPSAPPPPPPKLGTKLSPSGPNVPPTPALPTG--PLSSG--KGRMLRVNLKN-SPA 836

  Fly   630 KMSDKAFWVK---------------CQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVDKPTTLTK 679
            |......|:|               ..|...|.|..:.||...||:...::..|..:|  ::...
plant   837 KKLKPYHWLKLTRAVNGSLWAETQMSSEASKAPDIDMTELESLFSASAPEQAGKSRLD--SSRGP 899

  Fly   680 KNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRL 744
            |...:::::.:.|.|..|||  |...:..:.:...:|..:...|.::.::.||::.|..|.::.|
plant   900 KPEKVQLIEHRRAYNCEIML--SKVKVPLQDLTNSVLNLEESALDADQVENLIKFCPTREEMELL 962

  Fly   745 QEIKAKGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKK 809
            :......:.|...|.|...:.::.|:..:|...:||:.:...:.:::..:....:|.|:::||:|
plant   963 KGYTGDKDKLGKCELFFLEMMKVPRVETKLRVFSFKMQFTSQISELRNSLGVVNSAAEQVKNSEK 1027

  Fly   810 FSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNF 874
            |.:|::.||.|||.:|.|:...||.||::..|.|||.|:..:|:.||:|||..::.:|.|:.|:|
plant  1028 FKRIMQTILSLGNALNQGTARGAAVGFKLDSLPKLSETRARNNRMTLMHYLCKILAEKIPEVLDF 1092

  Fly   875 YDDLSHVNKASRVNMDAIQKAMRQMNSAVKNL--ETDLQNNKVPQCDDDKFSEVMGKFAEECRQQ 937
            ..:||.:..|:::.:..:.:.|:.:|..::.:  |..|..|..|  ....|::::.:|......:
plant  1093 TKELSSLEPATKIQLKFLAEEMQAINKGLEKVVQELSLSENDGP--ISHNFNKILKEFLHYAEAE 1155

  Fly   938 VDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRL 1002
            |..|..:...:.:....|..|:..||:|...|:..:.:..|...|..||.:|   .::||
plant  1156 VRSLASLYSGVGRNVDGLILYFGEDPAKCPFEQVVSTLLNFVRLFNRAHEEN---GKQLE----- 1212

  Fly  1003 QEAREQSAREQQERQQRKKAVVDMDAPQTQEGVMDSLLEALQTGSAFGQRNRQARRQRPA 1062
            .||::.:|    |:::.|...:|   .:.::.:.:.:.|.....|..|:......::|.|
plant  1213 AEAKKNAA----EKEKPKTGGLD---TEIKKPLNEEVKEEKTKTSGLGKEMSDRLKERTA 1265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:461886
		Drf_FH3	253..453	CDD:461885
		FH2	608..983	CDD:396655	94/391 (24%)
AT5G58160	NP_001318825.1	PTP_PTEN-like	16..189	CDD:350347
		PTEN_C2	197..336	CDD:463081
		FH2	835..1201	CDD:396655	88/371 (24%)