Protein Alignment CG2617 and RNF26

DIOPT Version :9

• Sequence 1: NP_001260636.1
• Gene: CG2617 / 35331
• FlyBaseID: FBgn0032877
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_114404.1
• Gene: RNF26 / 79102
• HGNCID: 14646
• Length: 433
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 89/436 - (20%)
• Similarity: 146/436 - (33%)
• Gaps: 178/436 - (40%)

  Fly     1 MLDALIRAAELVDLVLLRPLASVI----------DAVITGVYYFLWGSYLVGFCLVEGSRKGWNL 55
            :||.|....:|..|::...|||:.          ..|:|.:.:...|..|....|:|
Human    14 VLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRGVLLSLLALIE-------- 70

  Fly    56 LRCAVRNINEGIRDL---------GLITLDVADYF--YGGTKG------GLKNVLDFGHCISR-- 101
              ..||....|::.|         ||.:|.:..:.  :|..:.      |:.||:..||.:.|
Human    71 --AVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVLNVVSSGHALLRQA 133

  Fly   102 ------------FICNLLID---LGDGILWLLMLLPRAILFLWDCL------LDFVVHSIVAH-- 143
                        ::.|.|::   :|...|:.|      :|.|||.:      :..||.:.:||
Human   134 CDICAIAMSLVAYVINSLVNICLIGTQNLFSL------VLALWDAVTGPLWRMTDVVAAFLAHIS 192

  Fly   144 ----------------GLSLLNSAFR--ASIGLALLLVLYMFRRYVYLMLIYLLQRGRIEISTK- 189
                            .|.||.||.|  ||..|..|..|.:....:.:.:..|.....:.::|:
Human   193 SSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAVTVTVLHPDFTLRLATQA 257

  Fly   190 -TQSVYLWTHHKLQHFI-------------HNVWYVS------ENAGSAS--------------- 219
             :|.....::|:|:..:             ..||..|      .|.|.|.
Human   258 LSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASWPNRGGAPGAPQGDPMRVFSVRT 322

  Fly   220 ------PE------------------------------------------------RCVVCMAQS 230
                  ||                                                :||:|..||
Human   323 RRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKKCVICQDQS 387

  Fly   231 RNVVVMPCRHLCLCKECSLQLVL--LLEDRCPVCRHNITSFLSVYV 274
            :.|:::||||||||:.|:..|:.  :....||:||..|...|:||:
Human   388 KTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVYL 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2617	NP_001260636.1	zf-C3HC4_3	223..269	CDD:290631	21/47 (45%)
RNF26	NP_114404.1	mRING-HC-C3HC5_RNF26	378..425	CDD:319702	20/46 (43%)
		modified RING-HC finger (C3HC5-type)	380..421	CDD:319702	18/40 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4265
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7529
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006367
OrthoInspector	1	1.000	-	-		oto91364
orthoMCL	1	0.900	-	-		OOG6_113023
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9347
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.780