Protein Alignment lok and K02E10.7

DIOPT Version :10

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001360081.1
• Gene: K02E10.7 / 186892
• WormBaseID: WBGene00019321
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 343
• Identity: 87/343 - (25%)
• Similarity: 145/343 - (42%)
• Gaps: 62/343 - (18%)

  Fly   160 PNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDR 224
            |.|...|...:|.| .::.|:.||.:|.|.|...|.:..|.|:|...:..            .|.
 Worm    37 PVELTCLSNVVNGT-GISDKIASGRFGTVFLGTITDSMLQVAIKEYHETF------------HDA 88

  Fly   225 VL---NEAKIMK---NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLY 283
            ||   :|...::   ::.||.:|:...:....|.||.|:|| ....|.:.|:......|..:||.
 Worm    89 VLTAHDEGSTLQKIISIEHPAIVQTFSVSHFQDIVYKVMEF-HSWTLHDDILDKGKYDESQTKLV 152

  Fly   284 FYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPL--- 345
            ..|...|::|||.:.:.|..|...|:.|    :|.::|:||...|:|:.    ......|||
 Worm   153 LVQATRALEYLHAQNLCHGTLHTKNIFL----QENMVKISDIESSQFLN----WLPFSQTPLHIL 209

  Fly   346 -YVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKS 409
             ::|||  :.......|.:.|:|||||.:|...:|:.||..|......:.|:.|  ..|.|  ..
 Worm   210 PFIAPE--LHNQLSEVTSECDLWSLGVCIFVMATGSCPFILESRNTMMESIQAG--ILGSP--VL 268

  Fly   410 VSQRAKLLINQMLIVDPERRPSIDDVLQSSW-----------------LRDAPMLQK-------A 450
            .|.:.:.|:.|::.|:|..|.|:..:::..|                 :|:.|::.:       .
 Worm   269 ASDKIQSLVEQLIHVNPSERMSLKSLIEDDWMTSDLVWNYFISCHEDLIRELPVVDRFIPAESLE 333

  Fly   451 KRLMKLDGMEIEEENFLE 468
            |..::.||.||..|...|
 Worm   334 KSTVQRDGSEISIETLDE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA_CHK2	32..158	CDD:438718
		STKc_Chk2	167..441	CDD:270986	75/300 (25%)
K02E10.7	NP_001360081.1	Protein Kinases, catalytic domain	52..300	CDD:473864	72/274 (26%)