Protein Alignment lok and ulk2

DIOPT Version :10

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_002664661.4
• Gene: ulk2 / 100329702
• ZFINID: ZDB-GENE-090218-30
• Length: 1034
• Species: Danio rerio
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 166/319 - (52%)
• Gaps: 58/319 - (18%)

  Fly   162 ESIGLPEEINKTYYVNRK--LGSGAYGLV-RLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPD 223
            |::|       .:..:||  :|.||:.:| :..:..:|..:.|:|.:.|..||          ..
Zfish     2 ETVG-------DFEYSRKDLIGHGAFAVVFKGRHKKKTDWEVAIKSINKKNLS----------KS 49

  Fly   224 RVL--NEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQ 286
            ::|  .|.||:|.|.|..:|.::|:.:.|.||::|:|:..||||.:.:.:...|.||..:::..|
Zfish    50 QILLGKEIKILKELQHENIVALYDVQETPSSVFLVMEYCNGGDLADYLQAKGTLREDTLRVFLQQ 114

  Fly   287 MCHAVKYLHDRGITHRDLKPDNVLL------ETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPL 345
            :..|::.|:.:||.||||||.|:||      :::.....:|::|||.::::|.:.:..||||:|:
Zfish   115 IAAAMRILNSKGIIHRDLKPQNILLSYTGRKKSSINGIRIKIADFGFARYLQSNMMAATLCGSPM 179

  Fly   346 YVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSV 410
            |:||||:::   :.|..|.|:||:|.|::.||.|..||.       |...:..|..|
Zfish   180 YMAPEVIMS---QNYDAKADLWSIGTVIYQCLVGKPPFQ-------ANSPQDLRMFY-------- 226

  Fly   411 SQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEP 469
             ::.|.|:..   :..|..|.::|:|..       :||:.:: .::|........||||
Zfish   227 -EKNKSLVPN---IPRETSPQLEDLLLG-------LLQRNQK-DRIDFDTFFSHPFLEP 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA_CHK2	32..158	CDD:438718
		STKc_Chk2	167..441	CDD:270986	83/284 (29%)
ulk2	XP_002664661.4	None