Protein Alignment CG10481 and SYG1

DIOPT Version :10

• Sequence 1: NP_995731.1
• Gene: CG10481 / 35273
• FlyBaseID: FBgn0032827
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_012217.3
• Gene: SYG1 / 854764
• SGDID: S000001309
• Length: 902
• Species: Saccharomyces cerevisiae
• Alignment Length: 828
• Identity: 186/828 - (22%)
• Similarity: 303/828 - (36%)
• Gaps: 244/828 - (29%)

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVEK----------------------------AP 37
            |||...|....:||||.:|::|...|:.:|...||                            .|
Yeast     1 MKFADHLTESAIPEWRDKYIDYKVGKKKLRRYKEKLDAEEEQSSSYRSWMPSVSVYQTAFQQREP 65

  Fly    38 SGSRPSNDVAIG---------YYRNFEELFFNSCRV--ELTKVNYFFAHKQAEAHRKLATL---- 87
            ..||...|...|         ..|.|...|.....:  :|:|.|.|:.....|..:|...|
Yeast    66 GKSRSDGDYRSGPAFKKDYSALQREFVADFIEDWLISFQLSKCNEFYLWLLKECDKKFEVLQSQL 130

  Fly    88 -------NYQ---LDRRRAQQDPRGSTASRGSAS------------------------------- 111
                   ||:   |:|..:..|...|..:.|.|.
Yeast   131 HYYSLQKNYERDNLNRSSSNVDMSTSLYAAGLAGRSDSRVNSIDSDSRSVMYGSMPCTKEAKKPR 195

  Fly   112 ------------------SWSRQPEGKRKFPPIKKLRL--------------------------- 131
                              ||.     ||.|..::.||.
Yeast   196 LSLLAYCQKVLKDNRLLPSWP-----KRGFSLLQDLRQDASSRGRETFAFGASFLETMTTTQARN 255

  Fly   132 ----AMSEFYLSLIMLQNYQTLNMTAFRKICKKYDK--NLKSEAGFAWYEK--YVL----KSTLA 184
                |:.|:||.|.::::::.:|:|.|||:.||:||  :.:....|..|.:  |.|    .:.:.
Yeast   256 LLSNAIIEYYLYLQLVKSFRDINVTGFRKMVKKFDKTCHTRELTTFMSYARTHYTLFKHADANVQ 320

  Fly   185 ITLQLDRMISTTE-------------------------NMYTDYLANG--DRSEAMAKLRVPPLG 222
            :..|..:.|::::                         ..:|..|.|.  ||.....||:...:.
Yeast   321 LVAQKMQQITSSQPTPTSELSSAQRDKEPITWLETQITEWFTTALTNSPKDRKHNTHKLKKLTIQ 385

  Fly   223 HPTPP----------VHVFSAGLFLGLFLVSAILCFISYFAVDTSPEFRYTFVSLFRGPISG--- 274
            :....          |.:...||.:|:.:  .::.:..|..: :|.|..:|...||  |:.|
Yeast   386 YSISEQMVHRNNRSIVQMLVVGLGIGVSM--TLITYTLYLGI-SSEETSFTHKILF--PLWGGWY 445

  Fly   275 --VTFGFCLAINIKVYETVGVNQ--VLIFEVERRNAIGAMR----------ALEISSFFGYMCTL 325
              :...|...:|..::...|:|.  :::.|::.:|......          .|...:||...|.:
Yeast   446 MVLLIAFLFLVNCFIWHRTGINYRFIMLGEIQSKNGTQFFNNDFATSKIPLKLYFLTFFIVPCAV 510

  Fly   326 SILLYLLHKEFFIEDPIYIPLVQVAFVVVLFLNPFRILFYSGRI-----WLLTVMGRILLSPFFF 385
            ..:|     .|.:|....:..:.:..|..|||.|..::.|..::     ||:..:.|:::|.||.
Yeast   511 CSML-----SFALEKLTPLGFLYIGIVSFLFLCPSGLIPYWDKVVHTRKWLVVTLIRLMMSGFFP 570

  Fly   386 VNFADFWVADQWTSLVVTIVDHYYLVRFYVRYFLDRSDAFEFEPDYAVAVIRCLPAWFRFAQSLR 450
            |.|.||::.|...||..:|.|   :..|:..|....::........|:.|:.|||:::||.|.||
Yeast   571 VEFGDFFLGDIICSLTYSIAD---IAMFFCVYSHTPNNLCGSSHSRAMGVLSCLPSYWRFMQCLR 632

  Fly   451 RFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHY--TDLFESPWTWAYITICIVSSIYTV 513
            ||.|||. ...:|:||.||.|.||       ...|:..|  :|..|...| .:|....::||.|.
Yeast   633 RFADSGD-WFPHLLNAAKYTLGIA-------YNATLCAYRLSDRSEQRRT-PFIVCATLNSILTS 688

  Fly   514 FWDLLMDFGLFRVWNGENKFLRDNLVY---PRW-----------FYYFVIVENTLLRCVWILEFA 564
            .|||:||:.........|..|||:|..   ..|           .|||.::.:.|:|..||: :|
Yeast   689 AWDLVMDWSFAHNTTSYNWLLRDDLYLAGKKNWENGSYSFSRKLVYYFAMIWDILIRFEWIV-YA 752

  Fly   565 LVHQELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRD 612
            :..|.:........::...|:.|||.|...|:||||:.|...||.|.|
Yeast   753 IAPQTIQQSAVTSFILALLEVLRRFVWIIFRVENEHVANVHLFRVTGD 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	55/293 (19%)
		EXS	267..601	CDD:460816	101/371 (27%)
SYG1	NP_012217.3	COG5408	1..310	CDD:227695	60/313 (19%)
		COG5409	402..803	CDD:227696	114/422 (27%)