DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and SHB1

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_194265.2	Gene:	SHB1 / 828638	AraportID:	AT4G25350	Length:	745	Species:	Arabidopsis thaliana

Alignment Length:	774	Identity:	209/774 - (27%)
Similarity:	323/774 - (41%)	Gaps:	205/774 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELK------QMIRNAVEKAPSGSRPS---------------- 43
            |:|||...:.|:|||:..|::|..||      |..||..:.....|.||
plant     1 MRFGKEFVSQMIPEWQEAYIDYAYLKTILQDIQASRNRSDSNNQSSTPSFARNLTRRYNRDALVS 65

  Fly    44 --NDVAIGYYR-----------------------NFEELFFNSCRVELTKVNYFFAHKQAEAHRK 83
              :|:.:....                       :||..||.:...|..|||.|:..|...|..:
plant    66 ENHDIVVNTVTRLEEGLETAAYETTFLKAGEAGGDFEVTFFRTLDREFNKVNNFYRLKVETARTE 130

  Fly    84 LATLNYQLDRRRA-------------------QQDPRGSTASRGSASSWSR-------------- 115
            ...||.|:|...|                   .:|..||.:..||:|..:.
plant   131 ALALNKQMDALIAFRHKVMDQNQKNPSVFDSVSEDINGSASEVGSSSKCTEHNVALADLMRNEDT 195

  Fly   116 ---------QPEGKRKFPPI--------------------------KKLRLAMSEFYLSLIMLQN 145
                     :....|:..|:                          |:|::|..|||..|..|:|
plant   196 SNESILERIRMNKTREITPLSAIKTILKVHKQDELKFTRDNLKEVEKRLQVAFIEFYQKLRHLKN 260

  Fly   146 YQTLNMTAFRKICKKYDKNLKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTDYLANGDRS 210
            |..||.:|..||.|||||..|..|. ..|.:.|.||.|:.:.::.:::...|:::.::.:|.:|.
plant   261 YSFLNASAVSKIMKKYDKIAKRNAA-KLYMEMVDKSFLSSSEEVHKLLLKVESIFIEHFSNSNRR 324

  Fly   211 EAMAKLRVPPLGHPTPPVH------VFSAGLFL--GLFLVSAILCFISYFAVDTSP---EFRYTF 264
            |.|:.||        |.::      .||.|.|.  |:.|:.|:...|....:..:|   .:..|.
plant   325 EGMSHLR--------PKINKERHLITFSTGFFFGCGISLIVALGLIIHARNIMGTPGQRTYMETM 381

  Fly   265 VSLFRGPISGVTFGFCL------AINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFGYMC 323
            ..|:|      .|||.:      |.||..:....||...||..::...:|....|.:|  || :.
plant   382 FPLYR------FFGFVVLHMDVYAANIYFWRRYRVNYSFIFGFKQGTELGYRHVLLLS--FG-LG 437

  Fly   324 TLSILLYLLH---------KEFFIEDPIYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRIL 379
            |||:...||:         |::.:...: |||..:..|:::.|.||.||:.|.|.:.|:|:.|.:
plant   438 TLSLCAVLLNLDMEMDAQTKDYRLVTEL-IPLFLLVLVIIIVLCPFNILYRSSRFFFLSVLFRCI 501

  Fly   380 LSPFFFVNFADFWVADQWTSLVVTIVDHYYLVRFYVRY-----FLDR-----SDAFEFEPDYAVA 434
            .:||:.|:..||::.||.||.|..:..    :.||:.|     |..|     :....|...|.:.
plant   502 AAPFYAVHLPDFFLGDQLTSQVQALRS----LEFYICYYGFGDFRYRRRNTCTSNIGFRTFYFIV 562

  Fly   435 VIRCLPAWFRFAQSLRRFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPW-- 497
            .:  :|.|.||.|.:||..:....|..|  |.:||.|.|......|.       ||....|.|
plant   563 AV--IPYWLRFLQCIRRMVEDRDLSHGY--NGIKYLLTIVAASLRTA-------YTLNRGSNWNI 616

  Fly   498 -TWAYITICIVSSIYTVFWDLLMDFGLFRVWNG-ENKFLRDNLVYP-RWFYYFVIVENTLLRCVW 559
             .|.:..   |::.|..:||:::|:||.:  .| :|.||||.|:.| :..||..:|.|.|||.||
plant   617 TAWVFSG---VATFYGTYWDIVLDWGLLQ--RGCKNSFLRDKLLVPHKTVYYAAMVLNVLLRLVW 676

  Fly   560 I-----LEFALVHQELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDI 613
            :     |:|:.:|:|.:.     :|:...||.||..|||.|||||||.|.|::||.:.:
plant   677 LQTVLDLKFSFLHRETMV-----ALMACLEIIRRGIWNFFRLENEHLNNVGRYRAFKTV 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	60/275 (22%)
		SPX	3..163	CDD:281146	60/274 (22%)
		EXS	267..601	CDD:281164	115/368 (31%)
SHB1	NP_194265.2	SPX_PHO1_like	2..286	CDD:269897	64/284 (23%)
		SPX	3..291	CDD:281146	65/288 (23%)
		EXS	382..718	CDD:281164	115/370 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940