Protein Alignment CG10631 and LOC1278927

DIOPT Version :10

• Sequence 1: NP_609998.1
• Gene: CG10631 / 35262
• FlyBaseID: FBgn0032817
• Length: 3781
• Species: Drosophila melanogaster
• Sequence 2: XP_061512762.1
• Gene: LOC1278927 / 1278927
• VectorBaseID: AGAMI1_009459
• Length: 1163
• Species: Anopheles gambiae
• Alignment Length: 1232
• Identity: 221/1232 - (17%)
• Similarity: 354/1232 - (28%)
• Gaps: 407/1232 - (33%)

  Fly   189 PYIKSEPMEAYQQPPNPM-------APPPAPEVLIKSEPIDEHSYKSNYIDDNTP---------- 236
            |..:..|..|:..||.|:       ..||.|..|:.....|....|.|..:.:.|
Mosquito    18 PPTQGPPQSAHPPPPQPIPIVKPEFKVPPIPAHLMDVRGPDGSLVKINMPEHHDPSKPPNNVEML 82

  Fly   237 ---FADFSKFSEFSE-------DMLS-PKVELTVKDESYGRTTS--------------------- 269
               ..|.|:|..:.|       |||: |...|.....:...|||
Mosquito    83 KVNIEDLSQFLSYHEVFGKLPSDMLTGPSASLVPSSSTNTATTSAHSNGKLNHIRPGPTGESPFK 147

  Fly   270 ------SFLRRKQQSD----RGNESLPICQRCKEVFFKKQVYLRHVAE---------SNCGIQ-- 313
                  ||.|::..::    ...||...|..|.:.|.:|:....||..         :.||.:
Mosquito   148 CSYCAKSFTRKEHLTNHVRQHTGESPYRCPYCGKTFTRKEHLTNHVRLHTGETPYQCTYCGKKFT 212

  Fly   314 --------------EYDFKCSTCPMSFMTTEELQRHKLHHRADRFFCHKYCGKHFDTIAECEAHE 364
                          |..|:|:.|...|...|.|..|...|..:..|...||.|.|........|.
Mosquito   213 RKEHLTNHVRLHTGETPFQCTYCEKKFTRKEHLTNHTRLHTGETPFQCSYCQKKFTRKEHLTNHV 277

  Fly   365 YMQHEYDSFVCNMCSGTFATREQLYAHLPQHKFQQRFDCPICRLWYQTALELHEH-RL---AAPY 425
            .:......|.|:.|...|..:|.|..|:..|..:..|.|..|:..:.....|..| ||   ..||
Mosquito   278 RLHTGETPFQCSYCQKKFTRKEHLTYHVRLHTGETPFQCSYCQKKFTRKEHLTNHVRLHTGETPY 342

  Fly   426 ---FCGKYYTGGQSSSASQSQAQQHQTNYKLQDCHMATMEMP----------------------- 464
               :|.|.:|           .::|.||:    ..:.|.|.|
Mosquito   343 QCTYCDKKFT-----------RKEHLTNH----VRIHTGETPYRCTYCEKKFTRKERLTYHIRWH 392

  Fly   465 --TTPHHKTTPSGSSLPATAALNSLLQQRQANADGAAMFAASAMKNEVNVKM-ERSYSNSTSESS 526
              .||:|.|               ..:::.|..:        .:.|.|.:.. |..|..:..|..
Mosquito   393 TGETPYHCT---------------YCEKKFARKE--------HLTNHVRLHTGETPYQCTYCEKK 434

  Fly   527 YSVQDSGYNNAYGSDSSMHAGAIAGPQAHSSTLDDSEDALCCVPLCGVRKSTSPTLQFFTFPKDE 591
            :|.::.         .::|.....|...::.|..|.:.:........:|..|..|....|:.:.:
Mosquito   435 FSRRER---------LTIHTRIHTGETPYACTYCDKKFSRKERLTYHIRLHTGETPYQCTYCEKK 490

  Fly   592 KYLNQWLHNLKMFHIPAASYANFRICSMHFPKR--CINRYSL--------CYWAVPTFNLGHDDV 646
            ....:.|.|....|.....|. ...|...|.::  ..|...|        |.:....|.
Mosquito   491 FTRKEHLTNHVRLHTGETPYP-CTYCEKKFTRKEHLTNHVRLHTGETPYQCTYCDKKFT------ 548

  Fly   647 ANLYQNRELTN--TFTTGEVARCSMPHCTSQRGESNLKFYNFPKDIKSLIKWCQNARLPVQAKEP 709
                :...|||  ...|||...    |||    ....||.. .:.:|:.|: ......|.|..
Mosquito   549 ----RKEHLTNHTRLHTGETPY----HCT----YCEKKFMR-KEHLKNHIR-LHTGETPYQCT-- 597

  Fly   710 RHFCSRHFEERCIGKFRLKPWAVPTLHLGAQYGKIHDNPKNLYVEEKRCCLNFCRRSRSSDFNMS 774
              :|.:.|..:              .||        .|...|:..|.....::|::
Mosquito   598 --YCQKKFTRK--------------EHL--------TNHTRLHTGETPYQCSYCQK--------- 629

  Fly   775 LYRFPRDEVLLRRWCYNLRLDPG------VYRGKNHKICSAHFI-KEAL--GLRKLSPGAVPTLH 830
              :|.|.|.|..    ::||..|      .|       |...|. ||.|  .:|         ||
Mosquito   630 --KFTRKEHLTN----HVRLHTGETPYTCTY-------CQKKFTRKEHLTNHVR---------LH 672

  Fly   831 LGHTDTFNIYENELWPPPTAPNSHSSGLQHQTQQHSS--QHSLQQQLHSKSYHRQSAASTSSSAS 893
            .|.|.....|..:.:.......:|:.....:|..|.:  :....::.|..::.|.....|....:
Mosquito   673 TGETPFQCTYCQKKFTRKEHLTNHTRLHTGETPYHCTYCEKKFMRKEHLTNHIRLHTGETPYQCT 737

  Fly   894 SANSHYVDPDLSASYLGLGASGSSAMNASDSMDVCCVPSCESKRHNNENITFHT--IPRRPEQMR 956
            .....:...:...:::.| .:|.|....|     .|..|...|.|...::..||  .|.:.|
Mosquito   738 YCGKKFTRKEHLTNHVRL-HTGESPYRCS-----YCNKSFTRKEHLKNHVRLHTGDSPHKCE--- 793

  Fly   957 KWCHNLKIPEEKMHKGMRICSLHFEPYCIGGCMRPFAVPTLNLGHDDDDIHRNPDVIKKLNIRET 1021
             :|:.....:|.::..||                         .|..|:.|
Mosquito   794 -YCNKTFTRKEHLNNHMR-------------------------QHSGDNPH-------------- 818

  Fly  1022 CCVAVCKRNRDR-DHANLHRFPSNVSLLTKWCGNLQRPVP-DGSKLFN----------------- 1067
            || .||.:...| :|...|...|:.......|....:..| .|:.||:
Mosquito   819 CC-NVCNKTFTRKEHLINHMSRSHTGERPFQCDECGKSFPLKGNLLFHQRSHTKGQPMDRPFRCD 882

  Fly  1068 ----DAICEVHFEERCLRNKRLEKWAVPTLSLGHENIPYPLPTPEQVTEFYSRPTAPNNGEEQGE 1128
                |.||:.|.                   :.|:.                    .:.||:...
Mosquito   883 MCPKDFICKGHL-------------------VSHQR--------------------SHTGEKNHH 908

  Fly  1129 C--CVET-CKRNPSVDDIKLYRPPEEASVLAKWAHNLQTESSQLTSMRICNLHFEAHCIGKRMRP 1190
            |  |.:: .:|...:..:|...|.....||.|..| ::.|.....|                 :|
Mosquito   909 CPQCSKSYVERGNMLRHMKKTHPDAVIPVLPKLPH-IKVEPKSTVS-----------------QP 955

  Fly  1191 WAIPT--LNLAGTIENLYENPEHSMLYKRRTHMKAKQSASVKPTWVPRCCLPHCRKVRALHN 1250
            .::.|  .....||.::..|..|...:......|.:|.:.:.  .:|   |||......||:
Mosquito   956 ASVVTSPAQATSTITSIISNNTHPSQHHHHIQPKMEQKSQIH--HLP---LPHQHPAHQLHH 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368	6/31 (19%)
		C2H2 Zn finger	319..339	CDD:275368	6/19 (32%)
		DM3	584..642	CDD:128933	11/67 (16%)
		DM3	683..738	CDD:128933	8/54 (15%)
		DM3	775..832	CDD:128933	16/65 (25%)
		DM3	945..1000	CDD:128933	8/56 (14%)
		DM3	1038..1096	CDD:128933	11/79 (14%)
		DM3	1145..1198	CDD:128933	9/54 (17%)
		THAP	1236..1308	CDD:214951	5/15 (33%)
		DM3	1349..1406	CDD:128933
		THAP	1424..1493	CDD:214951
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933
		DM3	1778..1831	CDD:128933
		DM3	1980..2033	CDD:128933
		DM3	2147..2202	CDD:128933
		DM3	2308..2365	CDD:128933
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3622..>3673	CDD:461662
		DM3	3690..3748	CDD:128933
LOC1278927	XP_061512762.1	None