Protein Alignment Hakai and Cbll1

DIOPT Version :10

• Sequence 1: NP_001260593.1
• Gene: Hakai / 35256
• FlyBaseID: FBgn0032812
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: XP_038968140.1
• Gene: Cbll1 / 314028
• RGDID: 1310703
• Length: 542
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 134/531 - (25%)
• Similarity: 184/531 - (34%)
• Gaps: 194/531 - (36%)

  Fly    63 EDSVMQEL-----DKDGELETPGALEEPLPHGALGAVAASGNMTPATQQPQVLQQVPPPVMSQTT 122
            :|.::..|     :||.||:...:      .|:||.:.....: |.....:...:|.|...:|.|
  Rat    41 QDKILNVLFLKLYNKDNELQGTNS------SGSLGGLDVRRRI-PIKLISKQANKVKPAPRTQRT 98

  Fly   123 ISLSLARAV--DMEA-DISQLE------APTFTTLSRGPPEPMLRLKWNHKVSLIGEKVLNPMIH 178
            :|...|:|.  |.|. |.::.:      ...|....|.|.    .|.|:.|::::|||...| :|
  Rat    99 VSRMPAKAAQGDEEGFDYNEEQRYDCKGGELFGNQRRFPG----HLFWDFKINILGEKDDTP-VH 158

  Fly   179 CCDQCDKPILVYGRMIPCKHVFCLKCA---RAEPIKSCPRCTDKVLRVEQSGLGTVFMCTHGGSR 240
            .||:|..||.|||||||||||||..||   ..:..|.||.|:|.|.|:||...|::|||:.
  Rat   159 FCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSI---- 219

  Fly   241 YGSSGCRRTYLSQRDLQAHINHRH------------------VAP-------------------- 267
              ..||:|||||||||||||||||                  :||
  Rat   220 --VQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPDRFIMPPDKHHMSH 282

  Fly   268 ---------QPPPLQ----------------PQPQLSAMAEQPKMTDLGGVGLGLELHKQRKLSE 307
                     .|||||                |..:||.....|:........:....|.    :.
  Rat   283 IPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHS----NL 343

  Fly   308 SSVPISVSASIASRPVLSRLPLTGGVGNIGSIGSIPPPGSAAAAQNAIHGGHSTLTLANLTRINN 372
            .:|||...:|..:|                   ..|||..|.|..:..:.|...::
  Rat   344 ITVPIQDDSSSGAR-------------------EPPPPAPAPAHHHPEYQGQPVVS--------- 380

  Fly   373 ANAQECHQGKASLHHTL-------------------------KKGTPHQSESVADASYYSS---- 408
                  |.     ||.:                         ..||||...|.|.....:|
  Rat   381 ------HP-----HHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPP 434

  Fly   409 -------VLASFGSAAGNPGSGPP---GGGATAAAQPA---NPSG-----------SHSAVGPGA 449
                   ::|.......:|..|||   .||....|.|.   ||:.           |.....||.
  Rat   435 ITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGG 499

  Fly   450 LIGGSTDAPTG 460
            :..|...||.|
  Rat   500 MSPGIWPAPRG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hakai	NP_001260593.1	RING-HC_HAKAI-like	178..229	CDD:438171	30/53 (57%)
		zf_Hakai	229..264	CDD:465753	21/34 (62%)
Cbll1	XP_038968140.1	RING-HC_HAKAI-like	158..212	CDD:438171	30/53 (57%)
		zf_Hakai	212..243	CDD:465753	23/36 (64%)