DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10166 and dpm-1

DIOPT Version :9

Sequence 1:	NP_609980.1	Gene:	CG10166 / 35240	FlyBaseID:	FBgn0032799	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_499931.2	Gene:	dpm-1 / 176874	WormBaseID:	WBGene00022044	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	155/237 - (65%)
Similarity:	187/237 - (78%)	Gaps:	2/237 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TNGHKYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGEDK 67
            |:..||||::||||||:||||.||||..|:|.  :.:|||::||.|||||..:||.|||.||:||
Worm     2 TSTPKYSIILPTYNEKENLPICIWLIENYLKE--VSHEVIIVDDASPDGTQGIAKLLQKEYGDDK 64

  Fly    68 IVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSGTRYAGN 132
            |:::||..||||||||.||:..|.|:||:::|||||||||||||.|.||.:...|||:||||...
Worm    65 ILIKPRVGKLGLGTAYSHGLSFARGEFIILMDADLSHHPKFIPEMIALQHKYKLDIVTGTRYKDG 129

  Fly   133 GGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIASCVSKGYVFQMEMLVR 197
            |||.|||.|||.||:|||||:|.||.|..|||||||||||:|:|.|.||..|||||||||||:.|
Worm   130 GGVSGWDLKRKTISKGANFLAQFLLNPGVSDLTGSFRLYKRDILSKLIAESVSKGYVFQMEMMFR 194

  Fly   198 ARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYLFA 239
            |::.||.|.||||:||||.:|.||||..||:.:||.||||||
Worm   195 AKKSGYRIGEVPISFVDRFFGESKLGSQEIVDYAKGLLYLFA 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10166	NP_609980.1	PLN02726	3..241	CDD:215385	155/237 (65%)
CG10166	NP_609980.1	DPM1_like	10..237	CDD:133062	147/226 (65%)
dpm-1	NP_499931.2	PLN02726	1..235	CDD:215385	152/234 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159574
Domainoid	1	1.000	234	1.000	Domainoid score	I1345
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2865
Inparanoid	1	1.050	321	1.000	Inparanoid score	I1490
Isobase	1	0.950	-	0.830698	Normalized mean entropy	S787
OMA	1	1.010	-	-		QHG61609
OrthoDB	1	1.010	-	-		D1445102at2759
OrthoFinder	1	1.000	-	-		FOG0003124
OrthoInspector	1	1.000	-	-		oto20054
orthoMCL	1	0.900	-	-		OOG6_100818
Panther	1	1.100	-	-	LDO	PTHR43398
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4337
SonicParanoid	1	1.000	-	-		X2989
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890