DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment swm and AT3G27700

DIOPT Version :9

Sequence 1:	NP_001260586.1	Gene:	swm / 35235	FlyBaseID:	FBgn0002044	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_189407.2	Gene:	AT3G27700 / 822392	AraportID:	AT3G27700	Length:	908	Species:	Arabidopsis thaliana

Alignment Length:	1040	Identity:	229/1040 - (22%)
Similarity:	365/1040 - (35%)	Gaps:	373/1040 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 ADKENQPRDSRRRRASLRSRSRSRS---RSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQT 287
            :::|:..|:.:.||   :..:||:|   .|:::||    ||..|     |..|.:.|    |:..
plant    29 SEEEDDDRNHKHRR---KEETRSQSLEQDSSDQAF----SRPYR-----KNYRHYEN----GNSF 77

  Fly   288 DNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRS--HSRSMSP-----------ERNARRN----- 334
            .  .|.:|:|     |..:..|.:|.|.:.|.:  .||...|           :|::|.|
plant    78 S--EHEKRSF-----GTGSGQRVQFDNQRMRSNPMFSRDSGPGRGRGNYGSWAQRDSRFNPVDLS 135

  Fly   335 -------------------------QNSP---------------DRVQTAQANLIPAPVAPPAPV 359
                                     |::|               |.....|.:|.|       |:
plant   136 SHMVQVGSMGQGMFGGRGLAGVSAAQSAPWPPFGMIPGVPNGGLDGFHHLQGSLRP-------PL 193

  Fly   360 EHPASH--PRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYN-----PDAPE 417
            ..|.:.  ||||||||:|:|:|:||:.||.:||:|.:|.:.:      .|:.::|     |.||.
plant   194 NAPLNMGIPRQRCRDFEERGFCLRGDMCPMEHGMNRIVVDDV------QSLSQFNLPVSVPGAPH 252

  Fly   418 IWARS-------GGP----PPGA--------------GQGPVPP---------PTQP------GQ 442
            :.|.|       ||.    |.||              |.|...|         |.||      |:
plant   253 LAASSKQVPAQFGGASFMNPKGAHGRTNEGGMAVDGLGYGDAYPSAGGTDFYDPDQPLWNNSTGE 317

  Fly   443 T-----TINP--FSGNVRP------TTLMSGSGPSPMGVPNPADYARNPGAPPQA-------AMM 487
            |     |:|.  ...||.|      ....:|.|.......:.:.:.|..|:..||       |::
plant   318 TSGAISTLNSHGVDENVAPLDDSNQDAAENGCGIRDSRSTSQSVWGRMKGSNSQANSKEKADAVL 382

  Fly   488 PFPFNPTAVTTPLQRQLIPIPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPINSRLGPR 552
                |.:||.   :.||..:.|       ..:..||:....|....:.|         :|.:.
plant   383 ----NSSAVP---EDQLKEVSV-------NSSRHGKQNHVGESVAKVVD---------SSNIS-- 422

  Fly   553 VNPNMQQHNSSLELRKVPRGL--NTIAHLNN-------HFAKFGKIVNIQVSYEGDPEAAIVTFS 608
               |...:|:....:|..|.|  |.:.|.:|       ||.||||:::|.:..  :.|.|.|.||
plant   423 ---NDMMNNTRKPTQKAMRTLFVNYVPHESNRRDLILAHFQKFGKVIDIHIPV--NSERAFVQFS 482

  Fly   609 THAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPT 673
            ...||..|.|:.:||:.|||||::|.|..|..|.|...     |.|...|..|.
plant   483 KREEAESALRAPDAVMGNRFIKLWWANRDSIPDNGLST-----GSGASMKGRSM----------- 531

  Fly   674 PNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSG-- 736
             .|.||:  |..|:..|...|             ..|...|:.|...|         |||.|.
plant   532 -TASGAQ--NQFPIAAASKSN-------------HVSSIAKVPTFQTG---------GAPSSSEQ 571

  Fly   737 -RPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQRAP 800
             :|:....:...:...|:::...:.:|...||| |||:|:....:.:..|..:|:
plant   572 PKPVVVTTSGPKVTPLQQKKADTLERLKETLRK-KQEMLEQKRNEYRKKLATLEK---------- 625

  Fly   801 TLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQE 865
                                      |..:.::::..:|..|:.|       ||...:..|....
plant   626 --------------------------QGTVVKREEADEPDAKRVK-------LDTASDSGAAIAS 657

  Fly   866 GNDTTAIQKRLEELQRNLGVGSAANNKSTHYAPASGAPGGGAGRKRP-------NLP-EGPTRVD 922
            ....::..|::..|:      ..:..|.:...|   :|.....::||       |.| ....::|
plant   658 PKTESSTDKKVPILK------PLSTAKLSTETP---SPDSKNFKQRPYSFTTSLNAPMVNRYKLD 713

  Fly   923 RRPKAIVV-----TGFAAEEADFVLGHFKNFGEISK--------------HDVDREIPQLILSYA 968
            .|...|.|     ||.|  :...|..||.::||:||              |:...|.....:::.
plant   714 NRTTTIKVVPPLPTGLA--DVAVVKEHFSSYGEVSKVELEDNASIDSGKDHETQNESRAACVTFV 776

  Fly   969 TRLNAEQAVLRGKMYKDKRLQISW-------------------------------APVVTPAPAP 1002
            .|..||:|....|.:::..||:.|                               ...|:..|.|
plant   777 KRSAAEKAFANAKCWQEHTLQLVWVTRQSNRESNNNNNNSNSLSVSRDNLSSKNKCASVSNDPKP 841

  Fly  1003 MAAPVEKSAA--PGDMSVSLENPKQL-IQSVSES---------ESLLGSDTLPELRLEDEEEDEE 1055
             |..|:.|:.  |.:.:||.:|...| .|...||         ||:.|:..:......|||:.|:
plant   842 -AVEVKTSSTEEPENTNVSGDNDSTLDKQETKESDNDNNKSNHESIEGASEVIATAGTDEEQSEQ 905

Fly 1056 1055
plant 906 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:240703	30/81 (37%)
swm	NP_001260586.1	RRM2_RBM26_like	921..992	CDD:240704	23/89 (26%)
AT3G27700	NP_189407.2	ZnF_C3H1	<206..227	CDD:214632	12/20 (60%)
		RRM	365..>493	CDD:223796	38/157 (24%)
		RRM1_RBM26_like	437..508	CDD:409702	28/72 (39%)
		PRK12704	587..>644	CDD:237177	14/93 (15%)
		RRM_SF	712..800	CDD:418427	23/89 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2135
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I2242
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002919
OrthoInspector	1	1.000	-	-		oto3244
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14398
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1927
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050