Protein Alignment: swm and Rbm26

• Sequence 1: NP_001260586.1
• Gene: swm
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_001355612.1
• Gene: Rbm26
• MGIID: 1921463
• Length: 1012
• Species: Mus musculus
• Alignment Length: 1186
• Identity: 342/1187 (29%)
• Similarity: 506/1187 (43%)
• Gaps: 301/1187 (25%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            ||:||.:.||.|||..|||:||||.||||:||:||:|||||:|:||.:.|:||||||.:||..||
Mouse     5 MIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFV 69

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            |:||||:.::.||..|..|       |:..|.||     .:...:.||:            |:.:
Mouse    70 EKLFDAVNTKSYLPPPEQP-------SSGSLKVD-----FLQHQEKDIK------------KEEL 110

  Fly   131 IKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDQHKTKDSHNQQSASNYQHHH 195
            .|.:..:.|..:...                   |.|..:...:..::::|...:...|..:.:
Mouse   111 TKEEEREKKFSRRLN-------------------HSPPQSSSRYRDNRSRDERKKDDRSRKRDY- 155

  Fly   196 VRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRS 260
              ..:||.|.|                  |.|:.|      |||...||.|||||||..:...|.
Mouse   156 --DRNPPRRDS------------------YRDRYN------RRRGRSRSYSRSRSRSWSKERLRD 194

  Fly   261 RSRDR-RVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADD---------------- 308
            |.||| |...|.:|:.:.|:...|....|.......|:.......|...
Mouse   195 RDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVSNISSGHYPVPTLSSTITVIA 259

  Fly   309 RPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDF 373
            ....|||.     :.|.|.....:.:.||              .|.||.        |::||||:
Mouse   260 PTHHGNNT-----TESWSEFHEDQVDHNS--------------YVRPPM--------PKKRCRDY 297

  Fly   374 DEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPT 438
            ||||:|:||:.||:|||.:|||.|.:|    :..|..:....|.:   .|.||||.   |.|||
Mouse   298 DEKGFCMRGDMCPFDHGSDPVVVEDVN----LPGMLPFPAQPPVV---EGPPPPGL---PPPPP- 351

  Fly   439 QPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFN------PTAVT 497
                 .:.|...|:||.  :...||.|..:| |......|..|.|.:.|..|.|      ||.||
Mouse   352 -----ILTPPPVNLRPP--VPPPGPLPPSLP-PVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVT 408

  Fly   498 TPLQRQLIPIPV--------------VDG----AP--TGGVAEVGKRRFELED------TVAIAD 536
            |.:..|..|.|.              .||    ||  |.....:.:.|...:.      |....|
Mouse   409 TGIHHQPPPAPPSLFTAVFVLPDTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMD 473

  Fly   537 VPTKRKVPINSRL----------------------------GPRVN----PNMQQ------HNSS 563
            :|.:.|.|..|.:                            .|..|    |..|:      .|:.
Mouse   474 LPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVSTKKTWFDKPNFNRTNSPGFQKKVQFGNENTK 538

  Fly   564 LELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRF 628
            |||||||..||.|:.||.||::||.:||:||:|.||||.|::.|:|:.||..|..||||||||||
Mouse   539 LELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRF 603

  Fly   629 IKVFWHNDSSGADVGQMNQMGGGGGGGGR-----------KNASQYHLHNVPAVPTPNADGAKIS 682
            |||:||.:      |...|:........:           |.:.:..|..||:..|..|:....:
Mouse   604 IKVYWHRE------GTTQQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSATTEPAEAQSAT 662

  Fly   683 NANP--LTEAGA----GNIGTP---ATEQANTAA---------PASMRLKLNTTTAGGSAGGAAG 729
            :..|  :|:...    |.:..|   |||:..:.:         ||:::....|.:..
Mouse   663 SELPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLSVS-------- 719

  Fly   730 AGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVER---M 791
                      .||.:....:||::|..|    |...:||||||:|:.:::..|..:..:|:   |
Mouse   720 ----------TPAVDNNEAQKKKQEALK----LQQDVRKRKQEILEKHIETQKMLISKLEKNKTM 770

  Fly   792 DQQDPQRAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDME 856
            ..:|  :|..::|:::|...|.||:.|:|:          ....:..|...|||.|.:|||||.|
Mouse   771 KSED--KAEIMKTLEILTKNITKLKDEVKS----------TSPGRCLPKSIKTKTQMQKELLDTE 823

  Fly   857 LELIAQQQEGNDTTAIQKRLEELQ---RNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGP 918
            |:|..:.|.|.:.|.::::..|||   ...|:.|:...:..|......|.|.|.||.|.....|.
Mouse   824 LDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGTAHGRGRGRGRGRGVPGH 888

  Fly   919 TRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMY 983
            ..||.||:|:.::.|...:.:.:|.||..:|||....:|......|:::.||..||.|.:.|..:
Mouse   889 AVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDASLHAIITFKTRAEAEAAAIHGARF 953

  Fly   984 KDKRLQISW-APVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRL 1047
            |.:.|:::| .|:     |.|:|...:.|.|.:...             :.|||:....|.
Mouse   954 KGQDLKLAWNKPI-----ANMSAVDTEEAEPDEEEF-------------QEESLVDDSLLQ---- 996

  Fly  1048 EDEEEDEESEDRSWRR 1063
            :|:||:|::|.|||||
Mouse   997 DDDEEEEDNESRSWRR 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:240703	46/73 (63%)
		RRM2_RBM26_like	921..992	CDD:240704	22/71 (31%)
Rbm26	NP_001355612.1	PWI	11..74	CDD:351805	42/63 (67%)
		DUF1777	133..>165	CDD:312240	6/53 (11%)
		ZnF_C3H1	<294..314	CDD:214632	14/20 (70%)
		RRM1_RBM26	536..611	CDD:240960	47/75 (63%)
		Mnd1	<726..>821	CDD:335556	33/111 (30%)
		RRM2_RBM26_like	891..962	CDD:240704	22/71 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C334653172
eggNOG	1	0.900				E1_KOG2135
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2074
Isobase	1	0.950		0	Normalized mean entropy	S7344
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0002051
OrthoInspector	1	1.000				T616628
orthoMCL	1	0.900				OOG5_129444
Panther	1	1.100			O	PTHR14398
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3653
TreeFam	1	0.960
	13	12.740