Protein Alignment swm and rbm26

DIOPT Version :10

• Sequence 1: NP_001260586.1
• Gene: swm / 35235
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_002662309.5
• Gene: rbm26 / 619195
• ZFINID: ZDB-GENE-050706-50
• Length: 1007
• Species: Danio rerio
• Alignment Length: 1218
• Identity: 344/1218 - (28%)
• Similarity: 510/1218 - (41%)
• Gaps: 366/1218 - (30%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            ||:||.:.||.|||..|||:||||.||||:||:||:|||||:|:||.:.|:||||||.:||..||
Zfish     1 MIIENLEALKTWLSKTLEPICDADPSALAKYVVALVKKDKSEKELKALCIDQLDVFLQKETQTFV 65

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            ::||:|:.::.||..|..| ..||...|.:.|...|                 |....||.:|
Zfish    66 DKLFEAVNAKSYLPQPEQP-TPASRPETHQRTEKDE-----------------AKREEPPSRD-- 110

  Fly   131 IKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDQHKTKDSHNQQSASNYQHHH 195
                           :.||.:....|:.....:.....|::...|:.|...|..::...|
Zfish   111 ---------------EDREKKFSRRINHSPPSSSRYSRDSRRVDDRKKDDRSRKREYDRN----- 155

  Fly   196 VRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRS 260
                 ||.|.|                  |.::.|:    ||.|:...|||||||.|.:|...|.
Zfish   156 -----PPRRDS------------------YRERYNR----RRERSRSYSRSRSRSWSKDRTRDRD 193

  Fly   261 RSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSM 325
            |.|||   :|::::.:.|.:|...|::..|..|:..::                      |||
Zfish   194 RERDR---DRDRSRSRSRTRSRSRSRSRERDSGKPKYE----------------------HSR-- 231

  Fly   326 SPERNARRNQNSPDRVQTAQANLIPAP----------------VAPPAPVEH-----------PA 363
             |||        |:...|......|.|                :...||..|           |.
Zfish   232 -PER--------PEGATTDGYTAAPLPPVNSSAHFPVPTLSSTITVIAPTHHGNNTTESWSEFPQ 287

  Fly   364 SH--------PRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWA 420
            .|        ||:||||:||||:|:||:.||:|||.:|||.|.:|..|::    .:.|  |.:..
Zfish   288 DHTPFGRGGPPRKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPSIL----PFQP--PPLPG 346

  Fly   421 RSGGPPPGAG------------QGPVPPP-TQPGQTTINPFSG---------------------N 451
            ..|.||||..            :.||||| |.|  .::.|.:|                     :
Zfish   347 VDGPPPPGLPPPHALLTPPVNLRPPVPPPGTMP--PSLPPVAGPPPPLPALQPSGMDGPPNSITS 409

  Fly   452 VRPTTLMSGSGPSPMGVPNPADYARNPGAP----PQAAMMPFPFNPTAVTTPLQR--------QL 504
            ..||.:.||..| ||..|.|..:..:|..|    |:|        |:..:.|:.|        .|
Zfish   410 SVPTIVTSGIRP-PMTQPPPPLFTSDPFEPDVYNPEA--------PSMTSRPMYRHRVNAQRPNL 465

  Fly   505 IPIPV--VDGAPTGGVAEVGKRRFELEDT-----VAIAD--VPTK------------------RK 542
            |.:.:  :|..|...::.....|..||..     ..:.|  :|.|                  ||
Zfish   466 IGLTMAEMDLPPREKMSNSNNARIVLESDSRKRGAGLHDLAIPPKKPWFDKPNFSKPNHHGFHRK 530

  Fly   543 VPINSRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTF 607
            ||.     |..       |:.|.:.::|..||.|:.||.||:|||.|||:||:|..|||.|::.|
Zfish   531 VPF-----PLA-------NTKLAIGQIPPELNNISKLNQHFSKFGTIVNLQVAYNNDPEGALIQF 583

  Fly   608 STHAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLH------ 666
            :|..||..|.:|||||||||||:|.||.:.                       :..|:|
Zfish   584 ATPEEARRAIQSTEAVLNNRFIRVHWHRED-----------------------TVEHMHPKPHPS 625

  Fly   667 ----NVPAV--------------PTPNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRL 713
                ..|||              |||:.:.....:..|     ...:.....|:...:.|..:..
Zfish   626 VQPAQEPAVTALKQSVKDRLGPLPTPHPEPTPAPSGPP-----QNTLKASVKERLGFSKPPGLGT 685

  Fly   714 KLNTTTAG--GSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQS 776
            |:.:|:.|  .:....|...|...|.|.:.:.:|....|:::|..|    |...:||:|||:|:.
Zfish   686 KVLSTSTGLTKTVYNPAALKAGQKGAPFSASVSAEDALKRKQEAMK----LQQDVRKKKQEILEK 746

  Fly   777 YMKQMKTALELVER---MDQQDPQRAPTLQTIKVLQMTIDKLRKEIK--ADQDQLQAQMQQQQQQ 836
            :::..|..:..:|:   |..:|  :|..:||:..|..:|.||::|||  :..:.|:..:
Zfish   747 HIQTQKLLISRLEKNKSMKAED--KAQIMQTLTSLTNSITKLQEEIKGLSSANALRTTV------ 803

  Fly   837 QQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAI-----QKRLEELQRNL-----GVGSAANN 891
                  |:|.|.:|||||.||:|..:.|.|.||..:     |.:||..:|.|     |.|:.:..
Zfish   804 ------KSKAQAQKELLDTELDLYKKMQAGEDTAELKIKYTQLQLEAAKRGLLTPGRGRGAHSRG 862

  Fly   892 KSTHYAPASGAPGGGAGRKRPNLPEGPTR--VDRRPKAIVVTGFAAEEADFV--LGHFKNFGEIS 952
            :....:...|..|.|.|        .||.  ||.||:|:.::||:  |||.|  |.||..:|||.
Zfish   863 RGALRSRGRGIRGRGRG--------APTHAVVDHRPRALEISGFS--EADRVDLLPHFAQYGEIE 917

  Fly   953 KHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISW-APVVT-PAPAPMAAPVEKSAAPGD 1015
            ...::......|::|.||..||||.:.|....::.|:::| .|..: ....|..|..|....|.|
Zfish   918 DCQMEDSSLSAIITYKTRAEAEQAAIHGVRLNNQELRLAWHKPTASLNTTDPDEAEAEDEEFPED 982

  Fly  1016 MSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR 1063
            ..|              .:|||         .:|:||:|::|.|||||
Zfish   983 SLV--------------DDSLL---------QDDDEEEEDNESRSWRR 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:409702	40/72 (56%)
		RRM2_RBM26_like	921..992	CDD:409703	27/72 (38%)
rbm26	XP_002662309.5	None