Protein Alignment swm and Rbm26

DIOPT Version :10

• Sequence 1: NP_001260586.1
• Gene: swm / 35235
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_038949332.1
• Gene: Rbm26 / 306137
• RGDID: 1308297
• Length: 1017
• Species: Rattus norvegicus
• Alignment Length: 1183
• Identity: 346/1183 - (29%)
• Similarity: 508/1183 - (42%)
• Gaps: 290/1183 - (24%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            ||:||.:.||.|||..|||:||||.||||:||:||:|||||:|:||.:.|:||||||.:||..||
  Rat     5 MIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFV 69

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            |:||||:.::.||..|..|       |:..|.||     .:...:.||:            |:.:
  Rat    70 EKLFDAVNTKSYLPPPEQP-------SSGSLKVD-----FLQHQEKDIK------------KEEL 110

  Fly   131 IKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDQHKTKDSHNQQSASNYQHHH 195
            .|.:..:.|..:...                   |.|..:...:..::::|...:...|..:.:
  Rat   111 TKEEEREKKFSRRLN-------------------HSPPQSSSRYRDNRSRDERKKDDRSRKRDY- 155

  Fly   196 VRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRS 260
              ..:||.|.|                  |.|:.|      |||...||.|||||||..:...|.
  Rat   156 --DRNPPRRDS------------------YRDRYN------RRRGRSRSYSRSRSRSWSKERLRD 194

  Fly   261 RSRDR-RVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADD---------------- 308
            |.||| |...|.:|:.:.|:...|....|.......|:.......|...
  Rat   195 RDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVSNISSGHYPVPTLSSTITVIA 259

  Fly   309 RPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDF 373
            ....|||.     :.|.|.....:.:.||              .|.||.        |::||||:
  Rat   260 PTHHGNNT-----TESWSEFHEDQVDHNS--------------YVRPPM--------PKKRCRDY 297

  Fly   374 DEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPT 438
            ||||:|:||:.||:|||.:|||.|.:|    :..|..:....|.:   .|.||||.   |.|||
  Rat   298 DEKGFCMRGDMCPFDHGSDPVVVEDVN----LPGMLPFPAQPPVV---EGPPPPGL---PPPPP- 351

  Fly   439 QPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPAD---YA-----RNPGAPP-QAAMMPFPFN-- 492
                 .:.|...|:||.  :...||.|..:|...|   |:     ..|..|| |.:.|..|.|
  Rat   352 -----ILTPPPVNLRPP--VPPPGPLPPSLPPVTDDISYSLVLTGPPPPLPPLQPSGMDAPPNSA 409

  Fly   493 ----PTAVTTPLQRQLIPIPV---------VDG----AP--TGGVAEVGKRRFELED------TV 532
                ||.|||.:..|..|.|.         .||    ||  |.....:.:.|...:.      |.
  Rat   410 TSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTS 474

  Fly   533 AIADVPTKRKVPINSRL----------------------------GPRVN----PNMQQ------ 559
            ...|:|.:.|.|..|.:                            .|..|    |..|:
  Rat   475 GDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGN 539

  Fly   560 HNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVL 624
            .|:.|||||||..||.|:.||.||::||.:||:||:|.||||.|::.|:|:.||..|..||||||
  Rat   540 ENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYDEAKKAISSTEAVL 604

  Fly   625 NNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPTPNADGAKISNANPLTE 689
            |||||||:||.:      |..:|:         :..|...:.  |.|..|.....|.|....|..
  Rat   605 NNRFIKVYWHRE------GATHQL---------QTTSPKVIQ--PLVQQPILPVVKQSVKERLGP 652

  Fly   690 AGAGNIGTPATEQANTAAPASM-------RL------------KLNTTTAGGSAGGAAGAGAPGS 735
            ..:|.:.....:.|.:..|.::       ||            |:.:|:.|.:......|....:
  Rat   653 VPSGTVEPAEAQSATSELPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTGLTKTVYNPAALKAA 717

  Fly   736 GRPL---NPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVER---MDQQ 794
            .:.|   .||.:....:||::|..|    |...:||||||:|:.:::..|..:..:|:   |..:
  Rat   718 QKTLLVSTPAVDNNEAQKKKQEALK----LQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSE 778

  Fly   795 DPQRAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELEL 859
            |  :|..::|:::|...|.||:.|:|:          ....:..|...|||.|.:|||||.||:|
  Rat   779 D--KAEIMKTLEILTKNITKLKDEVKS----------TSPGRCLPKSIKTKTQMQKELLDTELDL 831

  Fly   860 IAQQQEGNDTTAIQKRLEELQ---RNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTRV 921
            ..:.|.|.:.|.::::..|||   ...|:.|:...:..|......|.|.|.||.|.....|...|
  Rat   832 YKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGAAHGRGRGRGRGRGVPGHAVV 896

  Fly   922 DRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDK 986
            |.||:|:.::.|...:.:.:|.||..:|||....:|......|:::.||..||.|.:.|..:|.:
  Rat   897 DHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAIITFKTRAEAEAAAVHGARFKGQ 961

  Fly   987 RLQISW-APVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDE 1050
            .|:::| .||     |.|:|...:.|.|.:...             :.|||:....|.    :|:
  Rat   962 DLKLAWNKPV-----ANMSAVETEEAEPDEEEF-------------QEESLVDDSLLQ----DDD 1004

  Fly  1051 EEDEESEDRSWRR 1063
            ||:|::|.|||||
  Rat  1005 EEEEDNESRSWRR 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:409702	45/72 (63%)
		RRM2_RBM26_like	921..992	CDD:409703	22/70 (31%)
Rbm26	XP_038949332.1	PWI	11..76	CDD:460224	43/64 (67%)
		ZnF_C3H1	<294..314	CDD:214632	13/19 (68%)
		RRM1_RBM26	541..616	CDD:409938	47/74 (64%)
		HEC1	<718..>842	CDD:444066	42/139 (30%)
		RRM2_RBM26_like	896..967	CDD:409703	22/70 (31%)