Protein Alignment: swm and Rbm27

• Sequence 1: NP_001260586.1
• Gene: swm
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_006525926.1
• Gene: Rbm27
• MGIID: 2147194
• Length: 1060
• Species: Mus musculus
• Alignment Length: 1302
• Identity: 329/1303 (25%)
• Similarity: 507/1303 (39%)
• Gaps: 481/1303 (37%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            |::|:.|.||.||:.:|||:||||.||||.||:||:||||.:|:||....:||||||.:||:.||
Mouse     1 MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFV 65

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            ::||:::.::.||. |..|:                                   .|.|.|
Mouse    66 DKLFESLYTKNYLP-PLEPV-----------------------------------KPEPKP---- 90

  Fly   131 IKPDSNQVK---LEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDQHKTKDSHNQQSA-SNY 191
            :..:..::|   .::.:::.|:.....:.|         |..::....:.:|::...:... .:|
Mouse    91 LVQEKEEIKEEVFQEPAEEERDTRKKKYPS---------PQKSRSESSERRTREKKREDGKWRDY 146

  Fly   192 QHHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERA 256
            :.::.|:..                        |.:|    .|.||.|:..||:||..|||..|:
Mouse   147 ERYYERNEL------------------------YREK----YDWRRGRSKSRSKSRGLSRSRSRS 183

  Fly   257 FRRSRSRD--RRVNEREKTQ-RQFRN---------KSPPGSQTDNRHHGRRNF--------DRRR 301
            ..||:.||  |.|..||::: :..||         .:||.|.::....|.::.        ....
Mouse   184 RGRSKDRDPNRNVEHRERSKFKSERNDLESSYVPVSAPPPSSSEQYSSGAQSIPSTVTVIAPAHH 248

  Fly   302 IGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHP 366
            .....:....:.||     ||.|.|..||                        ||         |
Mouse   249 SENTTESWSNYYNN-----HSSSNSFGRN------------------------PP---------P 275

  Fly   367 RQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQ 431
            ::||||:||:|:||.|:.|.:|||.:|:|.:.:    .:.||..:.|           ||||
Mouse   276 KRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEV----ALPSMIPFPP-----------PPPG--- 322

  Fly   432 GPVPPPTQPGQTTINPFSG---NVRPTTLMSGSGPSPMGVPNPADYARNP-----GAPPQAAMMP 488
              :|||..||. .:.|..|   ...|     |.||.|...|.|....|.|     |.||.:.::|
Mouse   323 --LPPPPPPGM-LMPPMPGPGPGPGP-----GPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLP 379

  Fly   489 FPFNPTAVTT-------------------------PLQRQLI----------------------- 505
            .|..|.:.::                         ||.:.|:
Mouse   380 IPRPPISQSSLINSRDQPGTSAVPNLAPVGARLPPPLPQNLLYTVSERQPMYSREHGAAASERLQ 444

  Fly   506 -------------------------------PIPVV------DG----APTGGVAEVGKRRF--- 526
                                           |.|:|      ||    ||:  :...|:.::
Mouse   445 LGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVPDTYEPDGYNPEAPS--ITSSGRSQYRQF 507

  Fly   527 -------------------ELEDTVAIADVPTKRKVPIN-------------SR----------- 548
                               :.....|...:.|:..||::             ||
Mouse   508 FSRAQTQRPNLIGLTSGDMDANPRAANIVIQTEPPVPVSVNSNVTRVVLEPESRKRAISGLEGPL 572

  Fly   549 -----LGPRVNPNM-------QQH--NSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGD 599
                 ||.:.|.|.       :.|  |:.||::|:|:.||.|..||.||:|||.||||||:::||
Mouse   573 TKKPWLGKQGNNNQSKPGFLRKNHYTNTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGD 637

  Fly   600 PEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDS-------SGADV--GQMNQMGGGGGGG 655
            ||||::.:.|:.||..|..|||||||||||:|.||.::       |.|.:  .|.:.:
Mouse   638 PEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPALQSSAQILLQQQHTL------- 695

  Fly   656 GRKNASQYHLHNVP------------AVPT------------PNADGAKISNANPLTEAGAGNIG 696
              .:.||.| |::|            :.|:            |...||.:.|..|:..    .:|
Mouse   696 --SHLSQQH-HSLPQHLHPQQVMVTQSSPSSVHGGIQKMMGKPQTSGAYVLNKVPVKH----RLG 753

  Fly   697 TPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAAS-------------- 747
            ..:|.|::|:.      .||.|      ||::|...|....|.:|....:|
Mouse   754 HASTNQSDTSH------LLNQT------GGSSGEDCPVFSTPGHPKTIYSSSNLKAPSKLCSGSK 806

  Fly   748 -------IRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDP-QRAPTLQT 804
                   ::||||..     :|...:||:|||:|:..::..|..:..:|:.....| :||..::|
Mouse   807 SHDVQEVLKKKQEAM-----KLQQDMRKKKQEMLEKQIECQKMLISKLEKNKNMKPEERANIMKT 866

  Fly   805 IKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDT 869
            :|.|...|.:|:.|:|.           ......|...|||.:.:|||||.||:|..:...|.||
Mouse   867 LKELGEKISQLKDELKT-----------SSTVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDT 920

  Fly   870 TAIQKRLEELQ---RNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTRVDRRPKAIVVT 931
            |.::|:|.:||   ..||:......|:.    :|...|.|.||.|.........||.||||:...
Mouse   921 TELRKKLSQLQVEAARLGILPVGRGKTI----SSQGRGRGRGRGRGRGSLNHMVVDHRPKALPGG 981

  Fly   932 GFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVV 996
            ||..||.|.:|.||....:.||                             :||:||||||
Mouse   982 GFIEEEKDELLQHFSATNQASK-----------------------------FKDRRLQISW---- 1013

  Fly   997 TPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSW 1061
                       .|...|   |:|.|..::.::. .|:|:   ||..  |..:|:|:::|.|.|||
Mouse  1014 -----------HKPKVP---SISTETEEEEVKE-EETET---SDLF--LHDDDDEDEDEYESRSW 1058

  Fly  1062 RR 1063
            ||
Mouse  1059 RR 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:240703	44/73 (60%)
		RRM2_RBM26_like	921..992	CDD:240704	23/71 (32%)
Rbm27	XP_006525926.1	PWI	7..72	CDD:295364	39/65 (60%)
		zf-CCCH	277..299	CDD:279036	13/22 (59%)
		RRM_RBM27	599..674	CDD:240961	45/75 (60%)
		FAM76	<749..883	CDD:292665	37/155 (24%)
		RRM_SF	971..1013	CDD:302621	23/71 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C334642253
eggNOG	1	0.900				E1_KOG2135
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2074
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D324834at33208
OrthoFinder	1	1.000				FOG0002051
OrthoInspector	1	1.000				T616628
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR14398
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3653
TreeFam	1	0.960
	12	11.900