Protein Alignment swm and rbm27

DIOPT Version :10

• Sequence 1: NP_001260586.1
• Gene: swm / 35235
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_005167991.2
• Gene: rbm27 / 100332262
• ZFINID: ZDB-GENE-110411-31
• Length: 1030
• Species: Danio rerio
• Alignment Length: 1230
• Identity: 344/1230 - (27%)
• Similarity: 496/1230 - (40%)
• Gaps: 367/1230 - (29%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            ||::|.|.||.||:.:|||:||||.||||.||:||:||||.:|:|:.:..:||||||.:|||.||
Zfish     1 MIIDNVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELRALCADQLDVFLQKETTGFV 65

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            ::||:.:.::.||..||               |.:|:.:.:.
Zfish    66 DKLFECLTTKNYLGPPA---------------VKEEVKIPVQ----------------------- 92

  Fly   131 IKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDA-----------KPAFDQHKTKDSHN 184
                    |||:..:.|                 ||..|.           :..|::.:.:|...
Zfish    93 --------KLEEKEETA-----------------HVEDDRENRRRRSPLRNRSDFNESRARDDRR 132

  Fly   185 QQSASNYQ-HHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRS 248
            :......: ..|::|    |.|                   |.|:.      .||..|.|.||.|
Zfish   133 RDDRKRREVDRHLKS----GES-------------------YRDRH------ERRGGSSRGRSYS 168

  Fly   249 RSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFG 313
            ||||..|:..|.:||:|..|:|                   |...|..|::.|
Zfish   169 RSRSRSRSGSRGKSREREHNQR-------------------RAEHRSKFEQER------------ 202

  Fly   314 NNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPV-----------APP------APVEH 361
                     :...|...:..:.::|...||....|:|.|:           |.|      |||..
Zfish   203 ---------KEAEPYNPSSAHMSNPHHQQTHPPPLLPLPLPQHQFPSSGSPAVPKAATVVAPVHL 258

  Fly   362 PAS-----------HP-----------RQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSL 404
            |.|           |.           :.||||:||||:|:||:.||:|||.:|::.:.:...::
Zfish   259 PDSTTESWSAYFTNHSDGKTFNKSNTLKHRCRDYDEKGFCIRGDLCPFDHGNDPLIVDDVTLPTM 323

  Fly   405 M----------MSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGN------VR 453
            :          |.|    |...|       ||||... |:||..||....|.|....      .|
Zfish   324 IPFPPPPALPRMPM----PPMTE-------PPPGMPM-PLPPHGQPPPPGIYPMPAGGPPAILSR 376

  Fly   454 PTTLMSGSGP-------------------SPMGVPNPADYARNPGAP-------------PQAAM 486
            ||..:..:||                   ||:.:|.... ..||..|             ||..:
Zfish   377 PTGGLLPTGPPLIPATGIDTPPHSRTSTSSPLALPGVGP-PPNPPPPLPTSSSSSSASLHPQYTL 440

  Fly   487 MPFPFNPTA-------VTTP-----------LQRQ---LIPIPVVDG------------APTGGV 518
            ..:.::|.|       :|.|           :|.|   ||.:...||            .|:...
Zfish   441 SEYNYDPEAYNPESPGLTGPGRAQYRHFIPRIQTQRPNLIGLTSGDGLNSRAANIVIQTEPSVTS 505

  Fly   519 AEVGKRRFELEDTVAIADVPTKRKVPINSRLGPRV------NPNM-QQH-----------NSSLE 565
            ....:.||..|.        ..||..:.|..||:|      .||. .||           |:.||
Zfish   506 VSNSEMRFNSEQ--------ENRKRCLPSTDGPQVKKPWMDKPNFNNQHKPTFPKKHYYVNTKLE 562

  Fly   566 LRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIK 630
            :|::||.||.|..||.||:|||.||||||.:.||||||::.::.:.||..|..|||||||||||:
Zfish   563 VRRIPRELNNITKLNEHFSKFGTIVNIQVVFGGDPEAALIQYTANDEARRAISSTEAVLNNRFIR 627

  Fly   631 VFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYH--LHNVPAVPTPNADGAKISNANPLTEAGAG 693
            |:||.:.:.....|        |.....|..|.|  .|.|.....|.|... ::...|...|..|
Zfish   628 VYWHREPTANTQEQ--------GPSQSTNPGQQHPPTHKVINKQHPAASYV-LNKTIPKHHAATG 683

  Fly   694 NIG-TPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQK 757
            ..| |.:||..:.:...|:.|...::...|.........|..|......|..|....||::|..|
Zfish   684 TAGITGSTEPTSPSQEPSVGLTPPSSLVKGPFSRTVLKAASKSLGKTGKALEAQEALKKKQEALK 748

  Fly   758 AVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDP-QRAPTLQTIKVLQMTIDKLRKEIKA 821
                |...:||:|||:|:..::..|..:..:|:.....| :||..::|:|.|...|.:|:.||..
Zfish   749 ----LQQDMRKKKQEMLEKQIECQKVLINRLEKNRGMKPEERANIMKTLKELTEKISQLKNEISP 809

  Fly   822 DQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQ---RNL 883
                 .||......|     .|:|...:|||||.||:...:...|.|||.:::||.:||   ..|
Zfish   810 -----TAQATANTTQ-----SKSKTDAQKELLDAELDFHKKLTSGEDTTDLKRRLGQLQVEATRL 864

  Fly   884 GVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTR---VDRRPKAIVVTGFAAEEADFVLGHF 945
            |:..|...|.: .||..|.   |.||.|.....|...   ||.||:|:.:.||..||.:.::.||
Zfish   865 GLIPAGRGKPS-LAPTRGR---GRGRGRNLRGRGGANHMVVDHRPRALSIIGFTQEEKEELMPHF 925

  Fly   946 KNFGEIS---KHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISW----APVVTPAPAPM 1003
            ..||||.   :||..    .:::::.||.:||.|..:|..:|.:.|||||    .|.|:..|...
Zfish   926 VKFGEIEELREHDAS----SVVMTFKTRSDAENAANQGAKFKGRILQISWYKPKTPSVSTEPEEE 986

  Fly  1004 AAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR 1063
            .:..|.:||.             |..::|..|..   .|||...||::||:|.|.|||||
Zfish   987 ESKEEVNAAG-------------IHVMTEPVSPF---LLPEEEEEDDDEDDEYESRSWRR 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:409702	43/72 (60%)
		RRM2_RBM26_like	921..992	CDD:409703	27/73 (37%)
rbm27	XP_005167991.2	None