Protein Alignment Alp12 and alpl

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: XP_031762314.1
• Gene: alpl / 100485467
• XenbaseID: XB-GENE-1010301
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 496
• Identity: 199/496 - (40%)
• Similarity: 283/496 - (57%)
• Gaps: 31/496 - (6%)

  Fly   103 VDLPKEQKE---WYDQGIDELQKA--VSRQFNRRRAKNVILFVGDGMGPNTVTAARILGVK---- 158
            |..|:::|:   |..|..|.|:.|  :.:..|...|||||:|:|||||..||||.|||..:
 Frog    17 VTFPEQEKDPKYWRRQAQDTLRDALLLLQNLNTNVAKNVIMFLGDGMGVPTVTATRILKGQMAGQ 81

  Fly   159 --EEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKE 221
              ||..|..::||.:.|.|||..:.|||||..||||...|||.|..|.||:|....|.|:.:  .
 Frog    82 PGEETQLEMDKFPHVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVNAAAVRGQCNTT--R 144

  Fly   222 DHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQL 286
            .:.|.:|||||:..|...|.|||||:.||||:|.|||..:|.|..:..||.||..|||.|||.||
 Frog   145 GNEVDSILKWAKQAGKSVGVVTTTRINHATPSAAYAHCVNRDWYSDLEMPKEAVEQGCKDIAWQL 209

  Fly   287 IEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWA-GQSKDGRDLIRDWRLKKADEGVSHAVVQ 350
            :...  .:|.|||||||:.:....|.....|.|..| |...||.:|.:.|..:|.::..:. .|.
 Frog   210 MHNV--PNIEVIMGGGRKYMYPRNTSDVEYPNDDKASGTRLDGLNLTQIWLDQKPNKQAAR-YVW 271

  Fly   351 NNRELWNLNGQDVDYVLGIFANGHLMYDHERDRS-DAGMPSLSNMTLKALEVLGNSDKGFLLVVE 414
            |.::|.::|.|:||::||:|....::|:.||:.: |   |||..|...|:::|..:.:||.|:||
 Frog   272 NRQQLLSVNPQEVDHLLGLFEPIDMLYELERNTTMD---PSLPEMVEMAIKILRKNPEGFFLLVE 333

  Fly   415 AGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDRGS 479
            .|.||..||.|.|.:||.|.::::.|:....|.....|    ||.:|||||||..|..|:..||:
 Frog   334 GGRIDHGHHEGKANQALHEAVQMDIAIGLAGSMTSEED----TLTVVTADHSHVFTFGGYTHRGT 394

  Fly   480 SILGLA-GNSKTEGTPYTTLTYGTSYQGFQ-VDPQTQSRKDPTADDITAWEYTQQAAINTDENLH 542
            ||.||| ..|..:..|:|::.||.. .|:: |:.|   |::.:..|.:...|..|:|:......|
 Frog   395 SIFGLAPAVSDVDQKPFTSILYGNG-PGYKLVNGQ---RENVSTVDFSHPNYLAQSAVPLRMETH 455

  Fly   543 GGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRD 583
            ||.||.:.|.|.|::|.||||||:|:.|.::||..||:.:|
 Frog   456 GGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYAACIGQNQD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	186/454 (41%)
alpl	XP_031762314.1	Alk_phosphatase	52..491	CDD:395188	187/454 (41%)