Protein Alignment Alp12 and alpi.2

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001116946.1
• Gene: alpi.2 / 100144722
• XenbaseID: XB-GENE-854953
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 204/526 - (38%)
• Similarity: 278/526 - (52%)
• Gaps: 65/526 - (12%)

  Fly    71 SALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQFNRRRAKN 135
            :|||:.|:    .||......|..:|.        .|..|.|.||..:.|:.|::......||||
 Frog    16 TALLLLAI----TVHPSTGVVVSSLEA--------EKNPKFWNDQAKETLKNALNLNPITHRAKN 68

  Fly   136 VILFVGDGMGPNTVTAARILGVK------EEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALF 194
            :|:|:|||||..|:.||||...:      ||.::..|:||.:.|.|.|..|.|||||..|.||..
 Frog    69 LIMFLGDGMGVTTIAAARIYQGQVEGQPGEENIMAMEKFPYVALSKVYNVDAQVPDSAGTGTAYL 133

  Fly   195 GGVKVNYETGGVDANVPLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHV 259
            .|||.|..|.||.|....|||.:|  :.:.|.:||..|::.|...|.||||||.||:|.|.|||.
 Frog   134 CGVKANSGTLGVSAAAIYGNCVSS--KGNEVTSILHRAKLAGKSVGIVTTTRVQHASPGAAYAHS 196

  Fly   260 PDRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGGGRQMLV------SDVTGSAADPL 318
            ..|.|..::.|.:.....||.|||.||:.   ...|:||:||||..:.      .:..||:||
 Frog   197 ASRNWYSDNEMTSAMINNGCKDIAYQLVH---NTDIDVILGGGRAYMYPAGTPDPEYPGSSAD-- 256

  Fly   319 DTWAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRELWN------LNGQDVDYVLGIFANGHLMY 377
               .|..:||.:|...|..|:          ||.|.:||      :|....||::|:|....:.|
 Frog   257 ---RGLRRDGLNLTDIWLSKR----------QNARYVWNKEQFNAVNVDTTDYLMGLFEPKDMKY 308

  Fly   378 DHERDRS-DAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAV 441
            :..|:.| |   |||:.||.||:.:|..:.|||.|.||.|.||..||.|||:::|:|.||.:.||
 Frog   309 ELNRNASLD---PSLAEMTEKAIRILSKNPKGFFLFVEGGRIDHGHHDGNAKQSLTEALEFDKAV 370

  Fly   442 ESTLSFLKSSD--RLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLTYGTSY 504
                  |:...  :.:|||.:|||||||..|..|:.|||:||.|||.:..::..|||:|.||..
 Frog   371 ------LRGGQLTQENETLTVVTADHSHVFTFGGYTDRGNSIFGLAPSLASDRKPYTSLLYGNG- 428

  Fly   505 QGFQVDPQTQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVA 569
            .|:.:....  |.:.|..:..:..|.||||:......|||.||.|.|.|..::||||.|||||:|
 Frog   429 PGYPLPDAI--RANITGVNTGSNSYLQQAAVPVVSETHGGEDVAIMAKGPQAHLFHGFHEQSYIA 491

  Fly   570 HAISYA 575
            |.::||
 Frog   492 HVMAYA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	187/463 (40%)
alpi.2	NP_001116946.1	Alk_phosphatase	66..500	CDD:395188	188/464 (41%)