Protein Alignment Ddc and Tdc2

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 479
• Identity: 248/479 - (51%)
• Similarity: 337/479 - (70%)
• Gaps: 4/479 - (0%)

  Fly    36 MEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIERVIM 100
            |::.||:.....||::|..|||.:.||||.|.|:||||:.|:|..||::||.|..:|:|:|..||
  Fly     1 MDSTEFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLRHLLPPEAPQEPEDWDQIMRDVEDKIM 65

  Fly   101 PGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPA 165
            ||||||..|:||||||..||:|:|:.|||...|.||||:|.|||||||||.:::|||||.:.||.
  Fly    66 PGVTHWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPD 130

  Fly   166 EFLAC-SGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQAHSS 229
            .|||. .|..||||||.:|||..||.:|.|:|:.||.:|..||..:|..:|.||:.|||.:|||.
  Fly   131 HFLALKEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSC 195

  Fly   230 VERAGLLGGVKLRSVQ-SENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGP 293
            ||:|.::..||||.:: .::..:||..:.:|:|:|..:||:||:...|||||.|||||.|.|.|.
  Fly   196 VEKAAMICFVKLRILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLPEIGK 260

  Fly   294 VGNKH-NLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVV 357
            ...:. .:|:||||||||::|||||.:.|:||||.|||||.||:||:|.|||||.:|::|...:.
  Fly   261 QLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDRIRLT 325

  Fly   358 NAFNVDPLYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQFGD 422
            :|..||||||||....:|.|||||.:||.||||:||||||||.||:..||.:||.|...||:|.:
  Fly   326 SALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQHYIRHHIKLAKRFEE 390

  Fly   423 LCVADSRFELAAEINMGLVCFRLKGSNERNEALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFT 487
            |.:.|.|||:..::.:||||||||||::.||.||..||..|.:|:|||.:.|.|.:|....::..
  Fly   391 LVLKDKRFEICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHMVPASVGDRYIIRFCAVAQNA 455

  Fly   488 QSEDMEYSWKEVSAAADE-MEQEQ 510
            .:||::|:|..:...|:| :|:||
  Fly   456 TAEDIDYAWDIIVDFANELLEKEQ 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	206/378 (54%)
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	206/378 (54%)