Protein Alignment Ddc and spl-2

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_505372.1
• Gene: spl-2 / 181859
• WormBaseID: WBGene00006418
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 490
• Identity: 90/490 - (18%)
• Similarity: 166/490 - (33%)
• Gaps: 145/490 - (29%)

  Fly    34 IDMEAPEFKD-FAKTM--VDFIAEYL-----------ENIRERRVLPEVK-PGYLKPLIPDAAPE 83
            ||.:..|.|| ..|::  ||...||.           |.:|...:..::: |.:|:..:..|...
 Worm    73 IDKQLNEVKDELEKSLRIVDRSTEYFTTIPSHSVGRTEVLRLAAIYDDLEGPAFLEGRVSGAVFN 137

  Fly    84 KPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTE 148
            : |..:|..:..|.|.  |...|.:|.:...||...                          ..|
 Worm   138 R-EDDKDEREMYEEVF--GKFAWTNPLWPKLFPGVR--------------------------IME 173

  Fly   149 LEVVMMDWLGKMLELPAEFLACSGGKGGGVIQGTASE----STLVALLGAKAKKLKEVKELHPEW 209
            .|||.|              .|:...|.....||.|.    |.|:|.|..:.:.||       ..
 Worm   174 AEVVRM--------------CCNMMNGDSETCGTMSTGGSISILLACLAHRNRLLK-------RG 217

  Fly   210 DEHTILGKLVGYCSDQAHSSVERAGLLGGVKLRSV-------QSENHRMRGAALEKAIEQDVAEG 267
            :::|.:     ......|::..:|.....:|:|.:       :.:..:|:.|..::......:..
 Worm   218 EKYTEM-----IVPSSVHAAFFKAAECFRIKVRKIPVDPVTFKVDLVKMKAAINKRTCMLVGSAP 277

  Fly   268 LIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICP-------EYRHLMKGI 325
            ..||      ||.     |.::..|.:|.::::.:||||...|  |:.|       .|...:.|:
 Worm   278 NFPF------GTV-----DDIEAIGQLGLEYDIPVHVDACLGG--FLLPFLEEDEIRYDFRVPGV 329

  Fly   326 E--SADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDP-----LYLKHDMQGSAPDYRHWQI 383
            .  ||||     ||:.|.....|.:..::...:.|.:..|.     :|....|:||...:   .|
 Worm   330 SSISADS-----HKYGLAPKGSSVVLYRNKELLHNQYFCDADWQGGIYASATMEGSRAGH---NI 386

  Fly   384 PLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQF---------------GDLCVADSRFELA 433
            .|        .|..:..:..|..:|:.|:..:..::.               .|:|:      ::
 Worm   387 AL--------CWAAMLYHAQEGYKANARKIVDTTRKIRNGLSNIKGIKLQGPSDVCI------VS 437

  Fly   434 AEINMGLVCFRLKGSNERNEALLKRINGRGHIHLV 468
            ...|.|:..:|.....:.....|..:.....:|::
 Worm   438 WTTNDGVELYRFHNFMKEKHWQLNGLQFPAGVHIM 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	76/415 (18%)
spl-2	NP_505372.1	DOPA_deC_like	130..493	CDD:99743	76/433 (18%)