Protein Alignment Ddc and hdc

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017947930.2
• Gene: hdc / 100497702
• XenbaseID: XB-GENE-979207
• Length: 672
• Species: Xenopus tropicalis
• Alignment Length: 473
• Identity: 243/473 - (51%)
• Similarity: 329/473 - (69%)
• Gaps: 2/473 - (0%)

  Fly    33 SIDMEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIER 97
            ||.||..|::...|.:||:|.:||..:|||||.|:|:|||::.|:||:||.:.|.|:.:.:|||.
 Frog    25 SITMEPEEYRKRGKELVDYICQYLSTVRERRVNPDVQPGYMRALLPDSAPVESESWERIFRDIED 89

  Fly    98 VIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLE 162
            :|||||.||.||..|||||...|:|:::.|||:.||.|:||||.:||||||||:.:||||.|||.
 Frog    90 IIMPGVVHWQSPHMHAYFPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLG 154

  Fly   163 LPAEFL-ACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQA 226
            ||..|| .....|||||:|.|.|||||:|||.|:..|:.|:|...|:.|:..:..:|:.|.|:||
 Frog   155 LPCHFLHHYPSSKGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDSDDSQLNSRLIAYASNQA 219

  Fly   227 HSSVERAGLLGGVKLRSVQ-SENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDE 290
            |||||:|||:..||:|.:. .||..:||..|:.|:|:|...||:|.:...|||||..||||||.|
 Frog   220 HSSVEKAGLISLVKVRFLPVDENFCLRGDTLKAAVEEDRKNGLVPVFVCATLGTTGVCAFDYLAE 284

  Fly   291 CGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSW 355
            .|||..:..||:|:||||||:||:|||:|.||.|::.||||.|||.|||:|:|||:|.|:||...
 Frog   285 LGPVCAREKLWLHIDAAYAGTAFLCPEFRTLMNGVDYADSFTFNPSKWMMVHFDCTAFWVKDKYK 349

  Fly   356 VVNAFNVDPLYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQF 420
            :...|:|:|:||:|...|:|.|:.||||||.||||:||||||:|.:||:|||||||.....||.|
 Frog   350 LQQTFSVNPIYLRHANTGAATDFMHWQIPLSRRFRSLKLWFVIRSFGVKNLQAHIRHGAELAKYF 414

  Fly   421 GDLCVADSRFELAAEINMGLVCFRLKGSNERNEALLKRINGRGHIHLVPAKIKDVYFLRMAICSR 485
            ..|..:|..||:.|:.::|||.|||||.|...|.:|..:...|.::||||.|.|...:|..:.|:
 Frog   415 ESLVTSDQMFEVPAKRHLGLVVFRLKGPNVLTEEVLAELTKSGKMYLVPATINDELIIRFTVTSQ 479

  Fly   486 FTQSEDMEYSWKEVSAAA 503
            ||..:|:...|..:..:|
 Frog   480 FTTRDDILRDWNLIRQSA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	205/377 (54%)
hdc	XP_017947930.2	Pyridoxal_deC	62..440	CDD:395219	205/377 (54%)