Protein Alignment Ddc and gad1a

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_002663350.1
• Gene: gad1a / 100329827
• ZFINID: ZDB-GENE-070912-472
• Length: 591
• Species: Danio rerio
• Alignment Length: 553
• Identity: 121/553 - (21%)
• Similarity: 209/553 - (37%)
• Gaps: 136/553 - (24%)

  Fly    44 FAKTMVDFIAEYLENIRERRVLP----------------EVKPGYLKPLIPDAAP---------- 82
            |.:|..||     .|:..|.:||                |:...|::.....:..
Zfish    85 FRRTETDF-----SNLYARDLLPAKNGEEYTMQFLLEVVEILTNYVRKTFDRSTKVLDFHHPHQL 144

  Fly    83 ------------EKPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIAC 135
                        ::||..:.::.|....:..||...| |:|.              :.||..:..
Zfish   145 LEGMEGFNLELCDQPESLEQILVDCRDTLKYGVRTGH-PRFF--------------NQLSSGLDI 194

  Fly   136 IGFT--WIASPACTEL---EV----VMMDWLGKMLELPAEFLACSGGKGGGVIQGTASESTLVAL 191
            ||..  |:.|.|.|.:   |:    |:|:.|  .|:...|.:....|:|.|:.....:.|.:.::
Zfish   195 IGLAGEWLTSTANTNMFTYEIAPVFVLMEQL--TLKKMREIVGWPNGEGDGIFSPGGAISNMYSV 257

  Fly   192 LGAKAKKLKEVKELHPEWDEHTILG-----KLVGYCSDQAHSSVERAGLLGG------VKLRSVQ 245
            :.|:.|...|:|          |.|     :||.:.|:.:|.|:::|..:.|      :.||:
Zfish   258 MVARYKHYPEIK----------IKGMAAAPRLVLFTSEHSHYSIKKASAVLGFGTENLILLRT-- 310

  Fly   246 SENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAG 310
            .|..|:..|.||..:.....:|.:|.:...|.|:|...|||.::|...:..|:|:|:|||.|:.|
Zfish   311 DERGRVIPADLEAKVIDAKQKGFVPMFVNATAGSTVYGAFDPINEIADICEKYNMWLHVDGAWGG 375

  Fly   311 SAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDPLYL-----KHD 370
            ...:..:::|.:.|||.|:|..:||||.|.|...|||:.:::...:....::...||     ::|
Zfish   376 GLLMSRKHKHKLSGIERANSVTWNPHKMMGVPLQCSAILVREKGLLQGCNSMCAGYLFQPDKQYD 440

  Fly   371 MQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELA-- 433
            :.....|.   .|..||.....|.|.:.:..|....:.||.|....::...........:|:.
Zfish   441 VTYDTGDK---AIQCGRHVDIFKFWLMWKSKGTTGFEKHIDRCLELSEYLYHKIKNREGYEMVFQ 502

  Fly   434 AEINMGLVCF-------RLKGSNERNEALLKRINGRGHIHLVPAKIK------------------ 473
            .|.....|||       ||....|..         |..:|.|..|||
Zfish   503 GEPQHTNVCFWYIPPSLRLLPDGEEK---------RHRLHKVAPKIKALMMECGTTMVGYQPQGE 558

  Fly   474 DVYFLRMAICSRFTQSEDMEYSWKEVSAAADEM 506
            .|.|.||.:.:......|:::...|:.....::
Zfish   559 KVNFFRMVVSNPAVTRSDIDFLIDEIERLGQDL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	98/431 (23%)
gad1a	XP_002663350.1	Pyridoxal_deC	141..515	CDD:395219	96/405 (24%)