Protein Alignment Ddc and gad3

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001083039.2
• Gene: gad3 / 100038790
• ZFINID: ZDB-GENE-070424-80
• Length: 546
• Species: Danio rerio
• Alignment Length: 512
• Identity: 122/512 - (23%)
• Similarity: 205/512 - (40%)
• Gaps: 92/512 - (17%)

  Fly    42 KDFAKTMVDFIAEYLENIRERRV----------LPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIE 96
            |.|.:.:|:.:..|:....:|..          |.|...|:...|     |::|:..:.::.|..
Zfish    66 KHFLQELVNILLAYISKSLKRSTKVLDFHYPHQLNEGLEGFSLEL-----PDQPDNLEQLLVDCR 125

  Fly    97 RVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKML 161
            ..:..||...| |:|.....|......:..:.|:.......||:..||....:|.|::..:..::
Zfish   126 DTLKYGVKTGH-PRFFNQLSTGLDIVGLAGEWLTSTANTNMFTYEISPVFILMEEVVLRKMHTII 189

  Fly   162 ELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTI--LGKLVGYCSD 224
            ..|.|       .|.|:.....|.|.|.::|.|:.       .|.|....|.:  :.:|..:.|.
Zfish   190 GWPEE-------DGDGIFCPGGSMSNLYSVLLARF-------HLFPAVKTHGMCAIPRLAMFTSA 240

  Fly   225 QAHSSVERAGLLGGVKLRSV----QSENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAF 285
            .:|.|::::..:.|:...:|    ..|..:|..:.|..:||:..::||:|||...|.|||...||
Zfish   241 HSHYSIKKSAAVLGIGTENVIVVRCDERGKMISSELNSSIEEAKSKGLVPFYVNATAGTTVYGAF 305

  Fly   286 DYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWL 350
            |.|.:...:...|.||:|||||:.|...:..::|..:.|||.|.|..:||||.|.|...||.:.:
Zfish   306 DPLHKIADICEHHGLWMHVDAAWGGGLLLSNKHRVKLHGIERAHSVTWNPHKMMGVPLQCSTILV 370

  Fly   351 KDPSWVVNAFNVDPLYLKHDMQGSAPDYRHWQ---------IPLGRRFRALKLWFVLRLYGVENL 406
            |....:.....:...||      ..|| :|::         |..||.....|||.:.:..|.|..
Zfish   371 KRKGLLQQCNQLCAEYL------FQPD-KHYEVSYDTGDKSIQCGRHVDIFKLWLMWKAKGSEGF 428

  Fly   407 QAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCFRLKGSNERNEA----LLKRING------ 461
            ::.: .||....::       ..::|....:..||   .||..|.:..    |.||:..
Zfish   429 ESQV-NHCLENAEY-------LYYKLKRRTDFQLV---FKGKPEHSNVCFWYLPKRVQNIPLGPE 482

  Fly   462 -RGHIHLVPAKIK------------------DVYFLRMAICSRFTQSEDMEYSWKEV 499
             ...:|:|..|||                  .|.|.|....:..||.||:::...|:
Zfish   483 REKELHMVAPKIKTKMMEEGFTMIGYQPLEDKVNFFRCVFSNPATQREDVDFLLDEI 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	96/390 (25%)
gad3	NP_001083039.2	Pyridoxal_deC	96..469	CDD:395219	101/410 (25%)