DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10700 and aifm1

DIOPT Version :9

Sequence 1:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001017244.1	Gene:	aifm1 / 549998	XenbaseID:	XB-GENE-1016872	Length:	636	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	77/363 - (21%)
Similarity:	153/363 - (42%)	Gaps:	53/363 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 FVVVGGGPSGAVCVETLRQEGFTGRLTLVCGEKHLPYDRTRIMNLL-----------------NT 181
            |:::|||.:......::|......|:.:|..|..|||.|..:...|                 |.
Frog   156 FLLIGGGTASFAAARSIRARDPGARVLIVSDESELPYMRPPLSKELWFSEDPHVTETLRFKQWNG 220

  Fly   182 YTKNLALREEQFY---------KDYGIEMQLGVSAERLDTNCNTLHCTNGKTFPYDKIYIATGYS 237
            ..:::..:...||         ::.|:.:..|.....:|...|.:...:|....|:|..||||
Frog   221 KERSIFFQPPSFYVPPEQLMSVENGGVSVLTGKKVVHMDVRENKVKLDDGTQISYEKCLIATG-- 283

  Fly   238 AVTPNIPGVH------LKNVKVIRNIGDARSIFKMVDKSTQVVCLGSSFMAVEATANLVSRARSV 296
            .|..::|.:.      .|...:.|.|.|.|::..:......:..:|..|:..|....|..:....
Frog   284 GVPRSLPAIERAGEEVTKRTTLFRRISDFRTLEAISSSVGSITIIGGGFLGSELACALGRKGTQT 348

  Fly   297 TLVARQNVPFKSTLGELIGQRI----LKLLEENKVDLRMSSGIIRILGNSRGEVVAVKLLDNSRI 357
            :|...|..|....:|:::.:.:    .:.::...|:: :|..:::.:....|: :.::|.|..::
Frog   349 SLEVIQMFPESGNMGKVLPEYLSHWTTEKVQREGVNV-LSDAVVKSVSYQNGK-LHIQLKDGRQV 411

  Fly   358 PCNLLILGTGCQCNTDFLQRSGININPN-GSVDVNDFLQTKVRNVYVGGDIANAY--ILGGFPDR 419
            ..:.::...|.:.||:..:.:|:.::.: |...||..||.: .||:|.||.|..|  .||    |
Frog   412 QTDHIVAAVGLEPNTELAKSAGLELDGDFGGYRVNAELQAR-NNVWVAGDAACFYDIKLG----R 471

  Fly   420 VNISHYGLAQYHGRIAALNMSGHIAKLEAIPFFYTVIF 457
            ..:.|:..|...||:|..||:|     .|.|:::..:|
Frog   472 RRVEHHDHAVVSGRLAGENMTG-----AAKPYWHQSMF 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	62/317 (20%)
		Pyr_redox	273..350	CDD:278498	11/80 (14%)
		COG3393	336..>508	CDD:225928	33/125 (26%)
		Reductase_C	464..527	CDD:291425
aifm1	NP_001017244.1	AIF-MLS	<67..>152	CDD:373428
		Pyr_redox_2	159..484	CDD:369639	67/333 (20%)
		AIF_C	487..616	CDD:373245	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43557
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100