DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10700 and aifm1

DIOPT Version :9

Sequence 1:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_005165182.1	Gene:	aifm1 / 373125	ZFINID:	ZDB-GENE-030826-11	Length:	748	Species:	Danio rerio

Alignment Length:	388	Identity:	81/388 - (20%)
Similarity:	157/388 - (40%)	Gaps:	62/388 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 FVVVGGGPSGAVCVETLRQEGFTGRLTLVCGEKHLPYDRTRIMNLL-----------------NT 181
            ::::|||.:......::|......|:.::..|..|||.|..:...|                 |.
Zfish   271 YLLIGGGTASFAAARSIRARDPGARVLIITEESDLPYMRPPLSKELWFSDDPKVTESLRFKQWNG 335

  Fly   182 YTKNLALREEQFY---------KDYGIEMQLGVSAERLDTNCNTLHCTNGKTFPYDKIYIATGYS 237
            ..:::..:...||         ::.|:.:........:|...|.:..::|....|:|..||||
Zfish   336 KERSIYFQPPSFYVSPADLAKVENGGVAVLTDSKVVHMDVRGNKVKLSDGSEISYEKCLIATG-- 398

  Fly   238 AVTPNIPGVH------LKNVKVIRNIGDARSIFKMVDKSTQVVCLGSSFMAVEATANLVSRARSV 296
            .|..|:..:.      :|...:.|.|.|.||:.|:..:...:..:|..|:..|....|..|:...
Zfish   399 GVPRNLQVIDRAGEEVIKRTTLFRKIEDFRSLEKISREVKSITIIGGGFLGSELACALGRRSADP 463

  Fly   297 TLVARQNVPFKSTLGELIGQRILKLLEE--NKVDLRMSSGIIRILGNSRGEVVAVKLLDNSRIPC 359
            .|...|..|.|..:|:::.:.:.....|  .|..:.:.:..:......:.:.:.:||.|...:..
Zfish   464 GLEVMQLFPEKGNMGKVLPEYLSNWTTEKVRKEGVNVITDAVVKNVTYKNDKLEIKLKDGRLVKT 528

  Fly   360 NLLILGTGCQCNTDFLQRSGININPN-GSVDVNDFLQTKVRNVYVGGDIANAY--ILGGFPDRVN 421
            :.::...|.:.:.:..:.:|:.::.: |...||..||.: .|::|.||.|..|  .||    |..
Zfish   529 DHIVAAVGLEPSVELAKSAGLEVDSDFGGYRVNAELQAR-SNIWVAGDAACFYDIKLG----RRR 588

  Fly   422 ISHYGLAQYHGRIAALNMSGHIAKLEAIPFFYTVIFGRAFRSAGYGPFKDV------VIDGSL 478
            :.|:..|...||:|..||:|     ...|:::..:|.     :..||  ||      ::|.||
Zfish   589 VEHHDHAVVSGRLAGENMTG-----ANKPYWHQSMFW-----SDLGP--DVGYEAIGIVDSSL 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	61/315 (19%)
		Pyr_redox	273..350	CDD:278498	12/78 (15%)
		COG3393	336..>508	CDD:225928	36/152 (24%)
		Reductase_C	464..527	CDD:291425	7/21 (33%)
aifm1	XP_005165182.1	AIF-MLS	<56..203	CDD:291623
		Pyr_redox_2	274..584	CDD:285266	61/312 (20%)
		Pyr_redox	439..523	CDD:278498	14/83 (17%)
		AIF_C	602..728	CDD:291391	13/50 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810