DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10700 and LOC100498581

DIOPT Version :9

Sequence 1:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_002936104.2	Gene:	LOC100498581 / 100498581	-ID:	-	Length:	530	Species:	Xenopus tropicalis

Alignment Length:	523	Identity:	207/523 - (39%)
Similarity:	322/523 - (61%)	Gaps:	20/523 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VCHKLEVQENEMRQVDASGIPSILLVKQSGILRAVGAMCPHRGAPLAKGVLSRNRVRCPWHGVCF 76
            :|.:.|:.|.|||:.|..| .:|||||.:|:..|||:.|.|.||||:|||||.||:||||||.||
Frog    11 LCEESELNEGEMREFDVQG-QTILLVKSNGVFTAVGSKCTHYGAPLSKGVLSGNRIRCPWHGACF 74

  Fly    77 NLETGDIENFPGLDSLPCHRVNVDSRGQVLVQVKRSYLLRHARIKSMACRNWQDQRHFVVVGGGP 141
            |:||||||.:||||||||..|.|:: |:||:...|..|....|:|.|:.....|:.:.|::|.||
Frog    75 NIETGDIEEYPGLDSLPCFEVTVEN-GKVLLNANRKALENPKRVKEMSRHYNGDRTNIVLIGSGP 138

  Fly   142 SGAVCVETLRQEGFTGRLTLVCGEKHLPYDRTRIMNLLNTYTKNLALREEQFYKDYGIEMQLGVS 206
            :..||.|||||||:.||:.:|..|||||||||::...:|...|::.||.|.|:..|.||:.....
Frog   139 AALVCAETLRQEGYKGRIVMVTREKHLPYDRTKLSKAMNVKAKDIYLRSEDFFSSYDIEVWTEKE 203

  Fly   207 AERLDTNCNTLHCTNGKTFPYDKIYIATGYSAVTPNIPGVHLKNVKVIRNIGDARSIFK-MVDKS 270
            ...::|:...:...:..|..|.::.||||........||..|:||.::|:..||.:|.: .:.|:
Frog   204 VVSINTDEGKVKFRDNSTLQYSQLLIATGSRPRELTCPGSSLQNVFLLRSPDDANAISEAAIGKN 268

  Fly   271 TQVVCLGSSFMAVEATANLVSRARSVTLVARQNVPFKSTLGELIGQRILKLLEENKVDLRMSSGI 335
              ||.:|:||:.:|..|.|..:|.||:::.|...||::.||..:|:..:|||:|..|.....:..
Frog   269 --VVIMGTSFIGMEVAAFLSDKASSVSVIGRSEFPFQAVLGPKVGEVAMKLLQEKGVSFYSRTEA 331

  Fly   336 IRILGNSRGEVVAVKLLDNSRIPCNLLILGTGCQCNTDFLQRSGININPNGSVDVNDFLQTKVRN 400
            ..|.|.: |:|..|.|.:.|::|.::::.|.|....::||:.|.|.::..|::.|:.|::|.|.:
Frog   332 REIRGEN-GQVREVVLRNGSKLPADVVVAGIGVTPASNFLKGSRIAVDTRGAIFVDQFMRTSVPD 395

  Fly   401 VYVGGDIANAYILGGFP------DRVNISHYGLAQYHGRIAALNMSGHIAKLEAIPFFYTVIFGR 459
            ||..||:.:      ||      .||||.|:.:|..|||||||||......::::|||:|.:.|:
Frog   396 VYAAGDVVS------FPLSIMEGHRVNIGHWQMAHSHGRIAALNMLNKQVPVDSVPFFWTSLLGK 454

  Fly   460 AFRSAGYGP-FKDVVIDGSLEDLQFVAYFFDDYDKVTAVASCGRDPMVAQFAELVSQGKELCRCQ 523
            :.|..|||. :..:.:.|:||:|:|:|::..| |.|.||:|...||:|||.||::|.|:.:.:.:
Frog   455 SLRYTGYGEGYTSIELKGNLEELKFLAFYIKD-DYVVAVSSMNYDPVVAQVAEVMSSGRRITKNE 518

  Fly   524 IVD 526
            :::
Frog   519 VLE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560	56/93 (60%)
		Pyr_redox_2	135..414	CDD:285266	96/279 (34%)
		Pyr_redox	273..350	CDD:278498	26/76 (34%)
		COG3393	336..>508	CDD:225928	64/178 (36%)
		Reductase_C	464..527	CDD:291425	24/64 (38%)
LOC100498581	XP_002936104.2	Rieske_AIFL_N	10..103	CDD:239560	56/93 (60%)
		Pyr_redox_2	129..427	CDD:400379	104/306 (34%)
		Reductase_C	447..524	CDD:405449	28/76 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H135034
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1777
OMA	1	1.010	-	-		QHG58553
OrthoDB	1	1.010	-	-		D183405at33208
OrthoFinder	1	1.000	-	-		FOG0001279
OrthoInspector	1	1.000	-	-		mtm9392
Panther	1	1.100	-	-	O	PTHR43557
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1666
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080