DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Swip-1 and efhd2

DIOPT Version :9

Sequence 1:	NP_001286079.1	Gene:	Swip-1 / 35158	FlyBaseID:	FBgn0032731	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001313422.1	Gene:	efhd2 / 571114	ZFINID:	ZDB-GENE-060531-152	Length:	233	Species:	Danio rerio

Alignment Length:	201	Identity:	114/201 - (56%)
Similarity:	144/201 - (71%)	Gaps:	4/201 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DSPSSTTNTDSSELTHILNRRQEIMESQEAGIEVRRTYKVVNVYTDFPEFSRNQIKDYQKTFNTY 81
            |.|  ||::..|||...|.||.|:.|.  .|...:.:.||.|.||:|.||||.||||.:|.|..|
Zfish    37 DKP--TTSSADSELGAKLQRRGELNEG--VGEHQQPSMKVFNPYTEFKEFSRKQIKDMEKMFKQY 97

  Fly    82 DTARDGFLDLQELKFMMEKLGAPQTHLGLKQMIAEVDEDNDGKISFREFLLIFRKAQAGELDSDS 146
            |:.:|.::||.|||.|||||||||||||||.||.|||||.|||:||||||||||||.||||..||
Zfish    98 DSEKDNYIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDLDGKLSFREFLLIFRKAAAGELAEDS 162

  Fly   147 GLNQLARLTEVDVEQVGVSGAKNFFEAKIEQQLRTNKFHDEIRAEQEERRREEEERAQRRQQFQQ 211
            ||:.||||:|:||...||.|||:|||||::....:|:|..|||.||||::::.||:.||:..|::
Zfish   163 GLHVLARLSEIDVSTEGVKGAKSFFEAKVQAINESNRFEAEIRLEQEEKKKQAEEKKQRQAAFKE 227

  Fly   212 RAAIFQ 217
            ..:.|:
Zfish   228 LKSAFK 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Swip-1	NP_001286079.1	EFh	73..131	CDD:238008	40/57 (70%)
efhd2	NP_001313422.1	EFh	89..147	CDD:238008	40/57 (70%)
efhd2	NP_001313422.1	EF-hand_7	90..147	CDD:290234	39/56 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580520
Domainoid	1	1.000	94	1.000	Domainoid score	I7431
eggNOG	1	0.900	-	-		E1_KOG0041
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32580
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3596
OMA	1	1.010	-	-		QHG52325
OrthoDB	1	1.010	-	-		D1511376at2759
OrthoFinder	1	1.000	-	-		FOG0003787
OrthoInspector	1	1.000	-	-		otm25375
orthoMCL	1	0.900	-	-		OOG6_105725
Panther	1	1.100	-	-	O	PTHR13025
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10220
SonicParanoid	1	1.000	-	-		X2644
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800