DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and thap3

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_001014316.1	Gene:	thap3 / 541481	ZFINID:	ZDB-GENE-050327-4	Length:	213	Species:	Danio rerio

Alignment Length:	234	Identity:	54/234 - (23%)
Similarity:	95/234 - (40%)	Gaps:	52/234 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAHCAVINCSHKYVHAG-SISFHRFPFKRKDLLQKWKEFTQRSAQWMPSKWSALCSRHFGDEDF 64
            ||..|:..||:::|.:.. .|:||||||.:..:|::|.:...|. .:.|.|...:||.||..:.|
Zfish     1 MPKSCSASNCTNRYNNKNPEITFHRFPFSKPSVLKQWLDNIGRD-DFQPRKHMVICSLHFTPDCF 64

  Fly    65 NCSNNRKTLKKNAVPSI-RVSEDD---------------SMSGHLEQVSPSNRPTHKQTLSSAAE 113
            :...|||.|..||||:: .|...|               |.|...:.::|...|...:.:....:
Zfish    65 SGLGNRKNLLWNAVPTLFAVPTQDANQNNFRKRLKRALQSASEKWDGITPDGLPLFTEEMHEDTQ 129

  Fly   114 SAATGVKATCRFCGSSAINCSSFDKSFELFGMIQKCFPTLQILQDDTLPKEICQECCLQLERFSQ 178
            .......|.|:   |:.:..:: |.::.|                        .:.|....|...
Zfish   130 DCNNNEVADCQ---STKVFAAA-DHTYAL------------------------SDACTTKARLFN 166

  Fly   179 FIDVVMLAQSELQRKYR--RQLKIK----QEPLVRVKQE 211
            .:|.....:..||.|.|  :::|:|    |..|:.::|:
Zfish   167 ILDANRWLRKRLQAKCRVIKRMKLKLKDAQRELLTLRQQ 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206	29/77 (38%)
		zf-AD	123..192	CDD:214871	8/68 (12%)
		zf-C2H2_6	674..700	CDD:290623
		C2H2 Zn finger	677..697	CDD:275368
		C2H2 Zn finger	705..726	CDD:275368
thap3	NP_001014316.1	THAP	4..82	CDD:283206	29/78 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10321
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001174
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910