Protein Alignment L2HGDH and mqo

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_416714.1
• Gene: mqo / 946702
• ECOCYCID: EG12069
• Length: 548
• Species: Escherichia coli
• Alignment Length: 521
• Identity: 111/521 - (21%)
• Similarity: 194/521 - (37%)
• Gaps: 151/521 - (28%)

  Fly    18 VGVAAPNESTATHKRSQHSSSSCGDYDLVVVGGGIVGAASAREIVLRHPSLKVAVLEKECKLAKH 82
            ||:.|.: ..|..|.|:...:     |::::||||:.|.....:....|...:.::|:...:|:.
E. coli    13 VGLNAVS-MAAKAKASEEQET-----DVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQE 71

  Fly    83 QSG--HNSGVIHAGIYYKPGTLKARLCVEGMHLAYAYLDEKKIPYKKTGKLIVATDEKEVKLLKD 145
            .|.  :|:|..|:.:               |.|.|.       |....|.:.:   ||.|.:.:.
E. coli    72 SSNGWNNAGTGHSAL---------------MELNYT-------PQNADGSISI---EKAVAINEA 111

  Fly   146 LE----------KRGI-------ANNVPDLRMIEGSE-----------IQEIEPYCQGVMALHSP 182
            .:          :||:       .|.||.:..:.|.:           :|:...: :| |.....
E. coli   112 FQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLF-RG-MRYSED 174

  Fly   183 HTGIVDWG-LVTE-------------------HYGQDFKQCGGDIYLDFNVS-------KFTETK 220
            |..|.:|. ||.|                   :||:..:|....:....|.|       :..:..
E. coli   175 HAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRN 239

  Fly   221 EGTDYPVTIHGAKPG--QTVRTKNV-LTCGGLQSDLLAEKTGCP--RDPRIVPFRGEYLLLTKE- 279
            :...:.||:...|.|  |.:|.|.| :..||....||.| :|.|  :|....|..|::|:....
E. coli   240 DDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQE-SGIPEAKDYAGFPVGGQFLVSENPD 303

  Fly   280 --KQHMVKGNIYPVPDPRFPFLGV-HFTPR-MDGS--IWLGPNAVLALK--REGYTWGDI----- 331
              ..|:.|  :|.......|.:.| |...| :||.  :..||.|..:.|  :.|..| |:
E. coli   304 VVNHHLAK--VYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLW-DLMSSTT 365

  Fly   332 --NLFEL-------FDALRYPGFVKMASKYIGFGLSEMSKSWFINLQIKALQKYIPDITEYDIQR 387
              |:..:       ||.::|     :.|:.:   |||..:       .:||::|.|...:.|.:.
E. coli   366 TSNVMPMMHVGLDNFDLVKY-----LVSQVM---LSEEDR-------FEALKEYYPQAKKEDWRL 415

  Fly   388 GPAGVRAQAMDLDG------NLVDDFVFDRGQGSGALAKRVLHCRNAPSPGATSSLAIAKMIADK 446
            ..||.|.|.:..|.      .|..:.|.|:   .|.:|..:     ..||||:::..|...:.:|
E. coli   416 WQAGQRVQIIKRDAEKGGVLRLGTEVVSDQ---QGTIAALL-----GASPGASTAAPIMLNLLEK 472

  Fly   447 I 447
            :
E. coli   473 V 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	98/481 (20%)
mqo	NP_416714.1	PRK05257	27..520	CDD:179979	106/506 (21%)