Protein Alignment L2HGDH and CG6415

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_609441.1
• Gene: CG6415 / 34474
• FlyBaseID: FBgn0032287
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 94/481 - (19%)
• Similarity: 157/481 - (32%)
• Gaps: 192/481 - (39%)

  Fly    34 QHSSSSCGD------YDLVVVGGGIV----GAA-----SAREIVLRHPSLKVAVLEKECKLAKHQ 83
            :|:||:.|:      ||..|..||.:    |.|     |.:.|:..|             |...|
  Fly    16 RHASSAAGEGQRTALYDFHVQKGGKIVNFGGYALPVQYSDQSIIASH-------------LHTRQ 67

  Fly    84 SGHNSGVIH---AGIYYKPGTLKARLCVEGMHLAYAYLDEKKIPYKKTGKLIVATDEKEVKLLKD 145
            .|....|.|   :.|:.|    .|..|:|.:..|    |....| :.:|.|.|.|:|.. .:|.|
  Fly    68 VGSIFDVSHMLQSRIFGK----DAAACLESVCTA----DILGTP-EGSGSLTVFTNEAG-GILDD 122

  Fly   146 LEKRGIANNVPDLRMIEGSEIQEIEPYCQGVMALHSPHTGIVDWGLVTEHYGQDFKQCGGDIYLD 210
            |    |.|           ::.|.|.|.....|:.....||:...:      .:||..|.|:.::
  Fly   123 L----IVN-----------KVSEKELYVVSNAAMKEQDMGIMKTAV------DNFKSQGKDVSIE 166

  Fly   211 FNVSKFTETKEGTDYPVTIHGAKPGQTVRTKNVLTCGGLQSDLLAEKTGCPRDPRIVPFRGEYLL 275
            |                                ||               |.|..:|..:|..
  Fly   167 F--------------------------------LT---------------PADQSLVAVQGPQ-- 182

  Fly   276 LTKEKQHMVKG-----NIYPVPDPRFPFLGVHFTPRMDGSIWLGPNAVLALKREGYTWGD---IN 332
            :.||...::.|     .:|        |:. .|...:.|.    ||  :.:.|.|||..|   |:
  Fly   183 VAKELSKLLTGKASLDQLY--------FMS-SFVTTLAGI----PN--VRITRCGYTGEDGVEIS 232

  Fly   333 LF-----ELFDALRYPGFVKMA------SKYIGFGLS-------------EMSKSWFINLQIKAL 373
            :.     :|.::|...|.:|:|      |..:..||.             |.:.:|.:..:.:..
  Fly   233 VASSQAQKLTESLLESGVLKLAGLGARDSLRLEAGLCLYGSDIDSKTTPVEAALAWLVTKRRRTT 297

  Fly   374 QKYIP--DITEYDIQRG--------------PAGVRAQAMDLDGNLVDDFVFDRGQGSGALAKRV 422
            :.: |  |:....::.|              |...|:...          :|.:||..|.:..
  Fly   298 RDF-PGADVILGQLKEGVSRRRVGLQMLGTKPPPARSGVA----------IFSQGQQVGQVTS-- 349

  Fly   423 LHCRNAPSPGATSSLAIAKMIADKIE 448
                ..|||.|..::|:. .:|:.::
  Fly   350 ----GCPSPSAGRNIAMG-YVAENLK 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	84/446 (19%)
CG6415	NP_609441.1	gcvT	3..403	CDD:476863	94/481 (20%)