Protein Alignment L2HGDH and Sardh

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_308638.5
• Gene: Sardh / 1269983
• VectorBaseID: AGAMI1_011026
• Length: 897
• Species: Anopheles gambiae
• Alignment Length: 435
• Identity: 97/435 - (22%)
• Similarity: 167/435 - (38%)
• Gaps: 86/435 - (19%)

  Fly    26 STATHKRSQHSSSSCGD-YDLVVVGGGIVGAASAREIVLRHPSLKVAVLEKECKLAKHQSGHNSG 89
            :.||..|...:.|...: .|:|::|||..|..:..::..|  .::..:|||. ||....:.|.:|
Mosquito    25 TAATSARKYSTESPLPESADVVIIGGGSAGCNTLYQLAKR--GVRAVLLEKS-KLTAGTTWHTAG 86

  Fly    90 VIHAGIYYKPGTLKARLCVEGMHLAYAYLDE--KKIPYKKTGKLIVATDEK---EVKLLKDLEK- 148
            ::..   .:|..::.||......|..:..:|  ....:...|.|.::...:   |...|..|.|
Mosquito    87 LVWR---LRPNDVEIRLLAATRDLLMSLEEETGHNSGWINNGGLFISHSPERLDEYSRLATLGKC 148

  Fly   149 RGIANNVPDLRMIEGSEIQEIEPYCQGVM---ALHSPHTGIVDWGLVTEHYGQDFKQCGGDIYLD 210
            .||.:::     :...:.|::.|......   ||:||..|:||..::.....:.....||.:..|
Mosquito   149 FGIESHI-----VGPEQAQKLFPPLDPTSFTGALYSPGDGVVDPAMMCTALTKGATANGGLVVED 208

  Fly   211 FNVSKFTETKEGTDYPVTIHGAKPGQ-TVRTKNVLTCGGLQSDLLAEKTG--CPRDPRIVPFRGE 272
            ..||:.. |.|.......:.|....: |:||..|:...|:....|.|..|  .|    ::|.:..
Mosquito   209 CTVSQII-TGENLLGMKDVRGVLTNKGTIRTNTVVNATGVWGRDLIEPLGVFLP----LIPMKHA 268

  Fly   273 YLLL-TKEKQHMVKGNIYPVPDPRFPFLGVHFTPRMDG-SIWLG--PNAVLALKREGYTWGDINL 333
            |::. |.:..|.:      :|:.|.....::|  |:.| ||.:|  .|..:.|.|   ..||.:
Mosquito   269 YVVSETMDTIHQM------LPNVRDHDFSLYF--RIQGKSICMGGYENNPIMLNR---VPGDFH- 321

  Fly   334 FELFDALRY-------PGFVKMASKYIGFGLSEMSKSWFINLQIKALQKYIPDITEYDIQRGP-- 389
            |.|:| |.|       .|.||:...:...|         |...|...:.:.||   :....||
Mosquito   322 FGLYD-LDYSVFDTHIQGAVKLCPAFGSAG---------IKSTICGPESFTPD---HKPLMGPDP 373

  Fly   390 --------AGVRAQAMDLDGNLVDDFVFDRGQGSGALAKRVLHCR 426
                    .|..:..|.|.|...:.           ||:.::|.|
Mosquito   374 TVSGLFHSVGYNSAGMMLGGGCAEQ-----------LAQWIIHDR 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	87/404 (22%)
Sardh	XP_308638.5	None