Protein Alignment L2HGDH and l2hgdh

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_002938171.1
• Gene: l2hgdh / 100145085
• XenbaseID: XB-GENE-5764342
• Length: 453
• Species: Xenopus tropicalis
• Alignment Length: 418
• Identity: 244/418 - (58%)
• Similarity: 309/418 - (73%)
• Gaps: 10/418 - (2%)

  Fly    43 YDLVVVGGGIVGAASAREIVLRHPSLKVAVLEKECKLAKHQSGHNSGVIHAGIYYKPGTLKARLC 107
            ||:|||||||||.||||:::||||:|:.||||||.::|.|||||||||||:||||.||:||||||
 Frog    39 YDVVVVGGGIVGLASARQLILRHPALRFAVLEKEKEIALHQSGHNSGVIHSGIYYTPGSLKARLC 103

  Fly   108 VEGMHLAYAYLDEKKIPYKKTGKLIVATDEKEVKLLKDLEKRGIANNVPDLRMIEGSEIQEIEPY 172
            |.|..|.|.|.|:|.||||:.||||||..:.|:..|:.|.:||:.||||.||:|...:|:|.|||
 Frog   104 VRGAALIYEYCDQKGIPYKQCGKLIVAVKQPEIPRLQALYERGLQNNVPGLRLIGAKDIKEKEPY 168

  Fly   173 CQGVMALHSPHTGIVDWGLVTEHYGQDFKQCGGDIYLDFNVSKFTETKE-------GTDYPVTIH 230
            |:|||||.||:||||::..|.:.|..||...||.:..||.|:......|       |.:|||.|.
 Frog   169 CRGVMALESPYTGIVNYKQVAQSYKDDFCDAGGSVLTDFEVTDIKMVNESPAGSVQGIEYPVAIK 233

  Fly   231 GAKPGQTVRTKNVLTCGGLQSDLLAEKTGCPRDPRIVPFRGEYLLLTKEKQHMVKGNIYPVPDPR 295
            ..| |:.|..|.||||.||.||.:::.:||..:||||||||:||:|..||.::|||||||||:||
 Frog   234 NNK-GEEVHCKYVLTCAGLFSDRVSQVSGCSAEPRIVPFRGDYLVLKPEKCYLVKGNIYPVPNPR 297

  Fly   296 FPFLGVHFTPRMDGSIWLGPNAVLALKREGYTWGDINLFELFDALRYPGFVKMASKYIGFGLSEM 360
            |||||||||||||||:||||||:||.|||||...|.|..:..:|:.|.|..|:..|.:.:|:.||
 Frog   298 FPFLGVHFTPRMDGSVWLGPNAILAFKREGYRLCDFNARDFKEAVTYSGLHKLVLKNLSYGMGEM 362

  Fly   361 SKSWFINLQIKALQKYIPDITEYDIQRGPAGVRAQAMDLDGNLVDDFVFDRGQGSGALAKRVLHC 425
            .:::|:|.|:|.|||:||:::..||.|||:||||||:|.|||||||||||  .|||.||..:||.
 Frog   363 YRAFFLNAQLKELQKFIPELSFNDIARGPSGVRAQALDRDGNLVDDFVFD--GGSGDLANCILHV 425

  Fly   426 RNAPSPGATSSLAIAKMIADKIENEFSI 453
            ||||||.|||||||::|||.::|..|.:
 Frog   426 RNAPSPAATSSLAISEMIASEVEERFGL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	231/397 (58%)
l2hgdh	XP_002938171.1	DAO	51..447	CDD:477422	231/398 (58%)