Protein Alignment CG10428 and Gstcd

DIOPT Version :10

• Sequence 1: NP_609918.1
• Gene: CG10428 / 35150
• FlyBaseID: FBgn0032724
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_080507.2
• Gene: Gstcd / 67553
• MGIID: 1914803
• Length: 634
• Species: Mus musculus
• Alignment Length: 661
• Identity: 220/661 - (33%)
• Similarity: 320/661 - (48%)
• Gaps: 123/661 - (18%)

  Fly     2 DQLYLEIEISTQKETTIY---TGVSSFLALFTYKFLKDPKNVRVNFVSTKIEGGKIALRSSQLKK 63
            :.|||  |.|.|.|..|:   |.|:.||..:.     :.|...|..|.|  |.......:|.||:
Mouse    11 ESLYL--EYSHQTEGCIFPLHTSVTLFLLSYC-----ECKVFNVCLVLT--EESTDTSDTSFLKE 66

  Fly    64 EL-TDRHITCRDAASLPAI-QDLKLPIYEKDGNTFI-AGTCAVCRELI-----ARQPNEELKKLL 120
            .| .|..|......:||.| |:..||......:.|. ||...|.|.:|     |....:|:.:||
Mouse    67 ALPQDLEIQVISKQALPPIVQNCCLPAVVDQPDVFCRAGLAVVLRHIIQKSYEAEPSRKEILELL 131

  Fly   121 GFKGSCLLAPSEASIWTKFCEVDLVAVVSKL--HSGQVLEFVPQEVVRFEQHMNEPVRMHNIYKQ 183
            |||.:||.|.:|.|.||:.||:.:...|...  .|.:....:|:|::..|:.::||||:||..|.
Mouse   132 GFKKTCLKACAEVSQWTRLCELTIPLAVENFLQESSEHPPTIPEEILELERKLSEPVRVHNDDKL 196

  Fly   184 AREQANQTE--------NGGKVKRRERVQIKCTTPKE--------ELLI---------------- 216
            .|::..|.:        ..||.|.:...|   .|||:        ||.:
Mouse   197 RRQKLKQQKAAGSEPPSGKGKAKSKASAQ---KTPKDLAAPSKSLELKVAFSKLTVQEDAAASNR 258

  Fly   217 ----------------EHRFAEGISFTIADIILYP----LLRIVFQHCGQMLPHFPLTSTWFSEI 261
                            ||.||||:.||:|||:|.|    .|.|:.:...:.|..|||.::|:..|
Mouse   259 EPSHIRKAKAADLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIICKKFSEKLEQFPLLTSWYQRI 323

  Fly   262 D------SFGDKCARVLRDLYVPQ----AIKTP--PGELGIPDCEATSLYKADPKRYKPRNRIYT 314
            .      :...||.  :..||:|:    |.|.|  ..|:...|.::..|:...|:
Mouse   324 QEVPKVKTAASKCG--IYFLYLPELLNSARKQPVNSDEVAAVDEQSDPLFIGGPR---------- 376

  Fly   315 SQLELEAALSKL--SSLQLQFNSDSEHTYGQQLIDWEQ----IEPTHAKSSALPKERLERKRQQL 373
                  ..::||  ..::..|   |.|......:||..    :.|...|.|.   :|..||:|||
Mouse   377 ------PTMTKLMEKGIEAMF---SPHPCPAWTLDWSSLPAAVSPKEGKMST---DRALRKQQQL 429

  Fly   374 ENLANAVVSLAQPGDRIVDFCSGTGHLAILLALKLPNCTIIVMENKAFSLLQAQKRSNELGLTNC 438
            .||...|::.|:|||||||||||.||:.|:||..||:|.:.::|||..||::|:|||:||||:|.
Mouse   430 NNLVYLVLNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI 494

  Fly   439 VFYQCNIDYFVGGFKIGASLHACGTATDIVLQQCRRAKAHFVCCPCCYGSLQPMPHISYPLSKAF 503
            .|.|.|::||.|.|.||.:|||||.|||:|::.|.:.:|.|:.||||||.:|.....::|.|:.|
Mouse   495 WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIQTRASFITCPCCYGFIQNTSKFNFPKSEKF 559

  Fly   504 QKVLDTKDYLYIAHSADQAHEMGTTNCKPETTLQGLHCMSVVDTDRLLQAEEAGYQVILTRLKPE 568
            :|.|..|:::.:...|||.    .....||..|.|..||.:||.||...|.|.||.|.:..::||
Mouse   560 KKTLSYKEHMLLCRFADQT----AVQLPPERRLIGKQCMGLVDLDRAAAAGEHGYSVQVISMEPE 620

  Fly   569 QCTPKNHLLVG 579
            .|:|||:::||
Mouse   621 SCSPKNNMIVG 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286	21/89 (24%)
		AdoMet_MTases	368..486	CDD:473071	66/117 (56%)
Gstcd	NP_080507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..233		13/46 (28%)
		GST_C_3	<271..330	CDD:464190	21/58 (36%)
		AdoMet_MTases	424..542	CDD:473071	66/117 (56%)