DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and ADR1

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_010502.3	Gene:	ADR1 / 851802	SGDID:	S000002624	Length:	1323	Species:	Saccharomyces cerevisiae

Alignment Length:	302	Identity:	62/302 - (20%)
Similarity:	125/302 - (41%)	Gaps:	54/302 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 EQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQRNKDRYTCKFCGKVFP 321
            |:.::|:...:   ||:|    |......|:|         :.|.::.||..|       ||:..
Yeast    29 EKQEIEMETDD---SPIL----LMSSSASREN---------SNTFSVIQRTPD-------GKIIT 70

  Fly   322 RSANLTRHL---------------RTHTGE-QPYKCKYCERSFSISSNLQRHVRNIHNKERPFKC 370
            .:.|:...:               ||.:|: :.:.|:.|.|:|:...:|:||.|: |..|:|:.|
Yeast    71 TNNNMNSKINKQLDKLPENLRLNGRTPSGKLRSFVCEVCTRAFARQEHLKRHYRS-HTNEKPYPC 134

  Fly   371 EICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFE-------EIRS 428
            .:|.|||.::..|.||.:|..|..:. ..:|...:....|.:..:|......|:       :..:
Yeast   135 GLCNRCFTRRDLLIRHAQKIHSGNLG-ETISHTKKVSRTITKARKNSASSVKFQTPTYGTPDNGN 198

  Fly   429 FMGKVTQQQQQQQQQQQHDQQQQQHQST--ATSASSSCSSSRDTPTSSHEEADHAPATSTADTAA 491
            |:.:.|...:::...:.:.:::...:.|  |:.::.|.||......||.|:........:.....
Yeast   199 FLNRTTANTRRKASPEANVKRKYLKKLTRRASFSAQSASSYALPDQSSLEQHPKDRVKFSTPELV 263

  Fly   492 PSSSRDQEEEDSQPI---MELKRTLTSKL-FPTTTADSAMTT 529
            |...::.|.:.|..:   ::|...|.|.. .....:||:.:|
Yeast   264 PLDLKNPELDSSFDLNMNLDLNLNLDSNFNIALNRSDSSGST 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	18/78 (23%)
		zf-C2H2	311..333	CDD:278523	4/36 (11%)
		C2H2 Zn finger	313..333	CDD:275368	4/34 (12%)
		zf-H2C2_2	325..349	CDD:290200	7/39 (18%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	8/19 (42%)
ADR1	NP_010502.3	zf-C2H2	104..126	CDD:395048	8/22 (36%)
		C2H2 Zn finger	106..126	CDD:275368	8/20 (40%)
		zf-H2C2_2	118..143	CDD:404364	12/25 (48%)
		C2H2 Zn finger	134..155	CDD:275368	9/20 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100