DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and Zbtb32

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001102987.1	Gene:	Zbtb32 / 688845	RGDID:	1584121	Length:	483	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	82/354 - (23%)
Similarity:	131/354 - (37%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 NHHA------KGKRRSSFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKE-- 135
            ||.|      ||.::|.|.:..:..|....:.    |.|.|:.:|.......|...|..:..|
  Rat   117 NHEAGLDPGWKGHQQSEFMRSSERGLGAPAER----QTPEEESSSEREQETPEEHKAPGESPEMA 177

  Fly   136 -----LNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIP 195
                 :..:..|.|.|.:|:..:......:..|.|...|......|      .:.||:||...:.
  Rat   178 GGRARMRGSEEALSPASMGYRGAETKQAEVMRGRASHRGSEESLRG------CSSPLSPPGSLLT 236

  Fly   196 AV--HPTLLEA--MTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPF-----RHP--LKKCE 249
            ::  .|...||  :.:..|..:..:   :.|.:..:|.:.|:|..|.:..     |.|  |..|:
  Rat   237 SLIPRPWWAEAPWLGEGQPALWSIL---LWPSRYGAPFSHSTPITAAWQVWPQDQRIPLTLNHCK 298

  Fly   250 LTWPPPTEQLQLELPHPNP--------KLSPVLPHPQLQDY---------QTRRKNKARTAATGG 297
            ..|    .:.||....|.|        ||||.......|.|         |.||.|      ...
  Rat   299 GLW----SENQLASSSPTPGSFPQGTEKLSPWEAEESGQGYTGTLATCVSQERRLN------CPS 353

  Fly   298 NATPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNI 361
            :..|.||...:.| |:|..|||.|.....:..|.|.||||:|:.|..|.:.....|.:.:|:|.
  Rat   354 HQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRT- 417

  Fly   362 HNKERPFKCEICERCFGQQTNLDRHLKKH 390
             :...|::|.:|........::..|::.|
  Rat   418 -HGAAPYRCPLCRAGCPSLASMQAHMRGH 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	22/63 (35%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	9/23 (39%)
		C2H2 Zn finger	341..362	CDD:275368	5/20 (25%)
		zf-H2C2_2	353..377	CDD:290200	5/23 (22%)
		zf-C2H2	368..390	CDD:278523	3/21 (14%)
		C2H2 Zn finger	370..390	CDD:275368	3/19 (16%)
Zbtb32	NP_001102987.1	BTB_POZ	13..112	CDD:365784
		COG5048	<272..>418	CDD:227381	44/157 (28%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		C2H2 Zn finger	398..418	CDD:275368	5/21 (24%)
		C2H2 Zn finger	425..445	CDD:275368	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000