DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment: CG10348 and prdm16

Sequence 1:NP_001286059.1 Gene:CG10348 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:XP_017950953.1 Gene:prdm16 XenbaseID:XB-GENE-991670 Length:1149 Species:Xenopus tropicalis

Alignment Length:570 Identity:175/571 (31%)
Similarity:239/571 (42%) Gaps:183/571 (32%)


  Fly     1 MREKD------HS--PRKMLPS-PKQGCVYPAL-------GLI----PTSYISHVPYDLASSASV 45
            |:||.      ||  |.:.||: |..  :|||.       .|:    |.|     |.||   ..|
 Frog   584 MQEKKMGSLPYHSMFPFQFLPNFPHS--LYPAFTDRTMNHNLLVKAEPKS-----PRDL---QKV 638

  Fly    46 AATSSSSTSPTTT------SATTTGRLQHQHSHQQHQTLNHHAKGKRRSSFDQPLDLRLAHKRKT 104
            .:|||.|....||      ||....|:....|                |..:|||||.::::.: 
 Frog   639 GSTSSESPFDLTTKPKEIKSALIPPRVLAPQS----------------SGEEQPLDLSISNRSR- 686

  Fly   105 DLVDQGPMEDENSNLIMFASELAVAQQKEKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGG 169
                                   .:|...:|...|||.:....:..||..|:             
 Frog   687 -----------------------ASQNGARETRRNHIYSDRKMMMNDMLSKI------------- 715

  Fly   170 GGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSP 234
                                ||..:|           :..||.|                |..||
 Frog   716 --------------------PQSQLP-----------QQPPLHY----------------AKPSP 733

  Fly   235 TGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQ---LQDYQTRRKNKARTAATG 296
            ...| |....::|.::|.|..|.:.:...|      ||:|.|||   :::...:.:|.|...|..
 Frog   734 FFMD-PIYSRVEKRKVTDPVGTMKEKYLRP------SPLLFHPQMSAIENMTEKLENFANLKADT 791

  Fly   297 GNATPNLP------------------QRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKY 343
            |::...||                  ::.|:||||::|||:||||||||||||||||||||:|||
 Frog   792 GSSLQPLPHHPFNFRSPPTTLSDSILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKY 856

  Fly   344 CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMH 408
            |:||||||||||||||||||||:||||.:|.|||||||||||||||||.:.|.:|..|||....|
 Frog   857 CDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENVPVSQHSGVITNHH 921

  Fly   409 CIRRFCEN----------PTEESYFEEIRSFMGKVTQQQQQQQQQQQHDQQQQQHQSTATSASSS 463
            .......|          ..|:|||.|||:|:.. ::..|.....::..:.|....|...|..:.
 Frog   922 GTSVSSPNSESENHALLDEKEDSYFSEIRNFIAN-SELNQTASLAEKRTEIQDIDSSKCLSLVNQ 985

  Fly   464 CSSSRDTPTSSHEEADHAPATSTA----DTAAPS----SSRDQEEEDSQP 505
            .....|.......|.|:...:.|.    :|.:||    .:.:::|||.:|
 Frog   986 KPDDADEEEDDELEEDYEDGSLTGKSQDETVSPSMENQETYEEDEEDEEP 1035

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 51/81 (63%)
zf-C2H2 311..333 CDD:278523 19/22 (86%)
C2H2 Zn finger 313..333 CDD:275368 17/20 (85%)
zf-H2C2_2 325..349 CDD:290200 22/24 (92%)
C2H2 Zn finger 341..362 CDD:275368 20/21 (95%)
zf-H2C2_2 353..377 CDD:290200 20/24 (83%)
zf-C2H2 368..390 CDD:278523 19/22 (86%)
C2H2 Zn finger 370..390 CDD:275368 17/20 (85%)
prdm16XP_017950953.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D254483at33208
OrthoFinder 1 1.000 FOG0001415
OrthoInspector 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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