DRSC/TRiP Functional Genomics Resources

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Protein Alignment: IFT46 and IFT46

Sequence 1:NP_609890.2 Gene:IFT46 FlyBaseID:FBgn0032692 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_064538.3 Gene:IFT46 HGNCID:26146 Length:355 Species:Homo sapiens

Alignment Length:354 Identity:98/355 (28%)
Similarity:145/355 (41%) Gaps:118/355 (33%)


  Fly    60 RRMFQNNSTDDDGLLQDIIDHDDEAE-DSEDDDDSEMQLPQGMTMGVGMTGLVPGPNMQKRPGSN 123
            :|.|..|..|||       |.||.:| ||:.|||.|                             
Human    77 QRGFSENEDDDD-------DDDDSSETDSDSDDDDE----------------------------- 105

  Fly   124 RSSKQVPDDTLSSGSEEAAMGGRMGSGGARGGAKLPHQKLTLPMRGSASGAGRSKRQDDQSFIMS 188
                           |..|                       |:.|:...|              
Human   106 ---------------EHGA-----------------------PLEGAYDPA-------------- 118

  Fly   189 ADKWEDLSVPGELKELFPYIVKYTPQTIDTPFHLQPFIPEFVPAVGDVDALLKVQAPPLLQPQRQ 253
              .:|.|.|..|:||||.||.:||||.||....|:||||:|:|||||:||.|||..|        
Human   119 --DYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRP-------- 173

  Fly   254 KDLNDHLEKLGLWLLDEPSGAQSEPSLLNMKLRSVLSGSMGRN-PRHASSASLVPTARSGKDIEK 317
               :...:.|||.:|||||..||:|::|::.|   ...|...| .:|....||....::.|.|:.
Human   174 ---DGKPDNLGLLVLDEPSTKQSDPTVLSLWL---TENSKQHNITQHMKVKSLEDAEKNPKAIDT 232

  Fly   318 WITEVEQVHMTQ---SMYDVQPRKDIDALLEDWPRSFGDEQTINALDQAYRSCLQQNISVAEYVG 379
            ||..:.::|.::   :::..:|..|||.|:::|...|.:.....:|..|...|     |:|||:.
Human   233 WIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDC-----SLAEYID 292

  Fly   380 VLCERFGVEGPLESQADYIHNVQTLFALY 408
            ::|....:  |:....  |.::..||:||
Human   293 MICAILDI--PVYKSR--IQSLHLLFSLY 317

Known Domains:


GeneSequenceDomainRegion External IDIdentity
IFT46NP_609890.2 IFT46_B_C 189..409 CDD:289115 77/225 (34%)
IFT46NP_064538.3 IFT46_B_C 116..318 CDD:289115 54/203 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C289287063
eggNOG 1 0.900 E1_2CDGQ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 146 1.000 Inparanoid score I4352
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 FOG0006294
OrthoInspector 1 1.000 T1074250
orthoMCL 1 0.900 OOG5_130568
Panther 1 1.100 LDO PTHR13376
Phylome 1 0.910 0.667 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R3191
TreeFam 1 0.960
User_Submission 00.000 Not matched by this tool.
109.780

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