Protein Alignment CG5790 and Cdc7

DIOPT Version :10

• Sequence 1: NP_609876.2
• Gene: CG5790 / 35095
• FlyBaseID: FBgn0032677
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_033993.2
• Gene: Cdc7 / 12545
• MGIID: 1309511
• Length: 564
• Species: Mus musculus
• Alignment Length: 577
• Identity: 189/577 - (32%)
• Similarity: 280/577 - (48%)
• Gaps: 114/577 - (19%)

  Fly   114 STIQAKDM----QSVDKNEEALK---------ELQESIPEINKIFDVHCRIGSGTFSTVLLGTLQ 165
            |:::..|.    .|:.|.|:::|         ||.|::|::..:|.:..:||.||||:|.|.|.|
Mouse     8 SSLRGSDRCPADDSLKKYEQSVKLSGIKRDIEELCEAVPQLVNVFKIKDKIGEGTFSSVYLATAQ 72

  Fly   166 RERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTH 230
            .:.|    ...:.|:||..||:||.||..||:|:...||.:||:|:..|.|.||:|...|||:.|
Mouse    73 LQEG----HEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEH 133

  Fly   231 DRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQRIA 295
            :.|.||..||:|.|:|:|:.||.:||:.:|:|.::||||||||.|||||..|:.|.||||||...
Mouse   134 ESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTR 198

  Fly   296 DD--------GSVVQSSDLSSREVFSIL-------RDLENGRSVTLTDGNSAQAEAEDYMARR-- 343
            |.        .|..|..|.|..:...::       |..........|...|.:........::
Mouse   199 DTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSRPAPKTVDQQCTPKTSVKRSYTQVHIKQGK 263

  Fly   344 --RMRALGGGGSVERAVTGPPSI------------QKLREQAG--GHLTKKDVANQRADTMRLLN 392
              :.|::  |.||:|:|.|..:.            :||.:|:.  ..:::|....:.|.:.:.:|
Mouse   264 DGKERSV--GLSVQRSVFGERNFNIHSSISHESPAEKLIKQSKTVDIISRKLATKKTAISTKAMN 326

  Fly   393 RLRLVSPNADP---------NNYVVSTNTSKKEMHASRAGTPGYRPPEVLLRYPKQSTAVDVWAA 448
            .:...:..:.|         ::.|.|...|:::..|.||||||:|.||||.:.|.|:||:|:|:|
Mouse   327 SVMRETARSCPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSA 391

  Fly   449 GVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLAQKVNTLDLRRVCMRF 513
            |||.||||||.:||:||..|..|||:|:.:.|.....:.|....:.:|.:::|...|||.:|.|.
Mouse   392 GVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCSKEVPAQDLRALCERL 456

  Fly   514 RHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFN-----CLCSNSGHNLERY------------- 560
            |..               |.||.  ||...|..|     ....|:.|...|.
Mouse   457 RGL---------------DSTTP--RSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLY 504

  Fly   561 ------------------DGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFSD 599
                              :|.|..|..|||||.:||::||..|||||.||.|.||.|
Mouse   505 KRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFFKD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5790	NP_609876.2	STKc_Cdc7	143..597	CDD:270921	176/531 (33%)
		Protein Kinases, catalytic domain	<238..>363	CDD:473864	48/143 (34%)
		Protein Kinases, catalytic domain	<427..597	CDD:473864	70/205 (34%)
Cdc7	NP_033993.2	STKc_Cdc7	50..429	CDD:270921	137/384 (36%)
		Protein Kinases, catalytic domain	<337..559	CDD:473864	81/238 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	460..506		10/47 (21%)