DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG5783 and TSC1

Sequence 1:NP_609869.1 Gene:CG5783 FlyBaseID:FBgn0032670 Length:287 Species:Drosophila melanogaster
Sequence 2:NP_000359.1 Gene:TSC1 HGNCID:12362 Length:1164 Species:Homo sapiens

Alignment Length:123 Identity:34/124 (27%)
Similarity:52/124 (42%) Gaps:27/124 (22%)


  Fly    57 AKQARDEGLFVIVDRYQL---------FVGCLNNTNG--LVGKALDLLDWSSGLKCSSIPSRHIG 110
            |:||....|..::|...|         |...||:..|  ||...:|..     |:.||.|:.|| 
Human     2 AQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYY-----LETSSQPALHI- 60

  Fly   111 ALDSLVESKKLNLVYRDCTNLFFMKANDALKLKVEPPSGFVLK-----SLSVADAPLV 163
             |.:|.|....:|:  |..|.:..||  |.:|.:....|.|::     ...::.|||:
Human    61 -LTTLQEPHDKHLL--DRINEYVGKA--ATRLSILSLLGHVIRLQPSWKHKLSQAPLL 113

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG5783NP_609869.1 Gly_acyl_tr_N <91..183 CDD:283638 22/79 (28%)
FR47 187..272 CDD:117022
TSC1NP_000359.1 Hamartin 7..719 CDD:282270 31/119 (26%)
Mediates interaction with WDR45B. {ECO:0000269|PubMed:28561066} 403..787
DUF4515 766..932 CDD:291649
Snf7 779..>881 CDD:304451
CENP-H 863..>957 CDD:283493
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 0.704428 Normalized mean entropy S1135
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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