Protein Alignment CG31741 and Scarb2

DIOPT Version :10

• Sequence 1: NP_724088.2
• Gene: CG31741 / 35079
• FlyBaseID: FBgn0051741
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_446453.1
• Gene: Scarb2 / 117106
• RGDID: 621882
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 115/480 - (23%)
• Similarity: 212/480 - (44%)
• Gaps: 45/480 - (9%)

  Fly     5 CCSVRQQKIWVFSMGG------LILAIGIFLASAWPAVSRQWIRSLLPLAPNSFIYNRWVTTPTP 63
            ||         |...|      |:.::.:.:|..:.....|.|...:.|...:.:::.|...|.|
  Rat     4 CC---------FYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLP 59

  Fly    64 VYSTVFLFNWTNPGDLNTEGVKPHFEQLGPYTFSDFKVKEDLEWNQPQVTYFGKRTWHFLPEKSN 128
            ||...:.||.|||.:: .:|..|..|::||||:.:.:.|.::::.:...|........::.|::.
  Rat    60 VYIQFYFFNVTNPEEI-LQGEIPLLEEVGPYTYRELRNKANVQFGENGTTISAVTNKAYIFERNQ 123

  Fly   129 GSLD---DVVIAPHFPTLTAALYSRRLRRILRKVMNFTLNREGGATHMTHTAGQWLFDGYYDHLL 190
            ...|   |::...:.|.||....::  :..||:::...|........:|||..:.|: ||.|.:|
  Rat   124 SVGDPTVDLIRTINIPLLTVVEMAQ--QPFLREIIEAMLKAYQQTLFVTHTVHELLW-GYKDEVL 185

  Fly   191 DFVEQLHSPLLPVYDNTFGWFYERNNSKTAEGNFTLHTGRGDLSQLGDLLLWNGENTTGFYPGE- 254
            ..|......:.|    .||.|||||.  |.:|.:...||..:......::.|||:.:..::..:
  Rat   186 SLVHIFRPDVSP----NFGLFYERNG--TNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWWTTDT 244

  Fly   255 CGKVNGSTGELWSPYRTWDQPTTIFLPDAAR--YLNLFPKENLTIDGIDVWRYESTNLTIDNGQL 317
            |..:||:.|:.:.|..:.|:...||..|..|  |:.....||  ::|:..:||:.....:.|
  Rat   245 CNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFEN--VEGLPAFRYKVPAEILAN--- 304

  Fly   318 SPDTECFCLKNRECPRNGVLDYGPPAFNGPFYMSHPHFFLTDQMYRENTTGLQPEESEHGMYVIM 382
            |.:...||:....|...|||:........|..||.|||:..|:.:.....|::|.:.||..:|.:
  Rat   305 SSENAGFCIPEGNCMDAGVLNVSICKNGAPIIMSFPHFYQADEKFVSAIKGMRPNKEEHESFVDI 369

  Fly   383 EPTLGIPLSLRGQLMISTKVVR-DEAIDL--FKNVAYDHYAPLFTMRLHAELDEGLTKLLKLALN 444
            .|..||.|....:..|:|.|.: |:.::.  .:.:.:    |:..:.....:|:.....||..:|
  Rat   370 NPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVF----PVMYLNESVLIDKETASQLKSVIN 430

  Fly   445 AAIIGMYTGIGLVLLGMSIVVTGIF 469
            ..:|  .|.|..:::.:.:....||
  Rat   431 TTLI--VTNIPYIIMALGVFFGLIF 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31741	NP_724088.2	CD36	19..471	CDD:460076	112/466 (24%)
Scarb2	NP_446453.1	CD36	28..457	CDD:460076	109/447 (24%)
		Important for interaction with GBA1. /evidence=ECO:0000250	155..191		10/36 (28%)