DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GCS2beta and GNPTG

DIOPT Version :10

Sequence 1:NP_609844.1 Gene:GCS2beta / 35056 FlyBaseID:FBgn0032643 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_115909.1 Gene:GNPTG / 84572 HGNCID:23026 Length:305 Species:Homo sapiens


Alignment Length:143 Identity:39/143 - (27%)
Similarity:60/143 - (41%) Gaps:30/143 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   431 VH----DGQCYNFEDREYVYTLCPFDRASQKSR-------SGGPETTLGRWDKWSGEPKQYSQQK 484
            ||    .|:|::..:..|.|..|||...:|..:       ||    .||.|.:|......::...
Human    62 VHLFRLSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSG----ILGIWHEWEIANNTFTGMW 122

  Fly   485 YTNGAACWNGPNRSAIINISCALEPKITAVSEPNRCEYYFEFETPAACD----------SEAFQS 539
            ..:|.|| ...:|.:.:.::|....::..||||:.|.|...||||..|.          .||.|.
Human   123 MRDGDAC-RSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVCHPHALLVYPTLPEALQR 186

  Fly   540 E----SENLHDEL 548
            :    .::|.|||
Human   187 QWDQVEQDLADEL 199

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GCS2betaNP_609844.1 PRKCSH-like 26..193 CDD:372423
SMC_prok_B <154..428 CDD:274008
PRKCSH 398..547 CDD:414904 36/140 (26%)
GNPTGNP_115909.1 PRKCSH 69..129 CDD:400321 15/63 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 267..305
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.